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  1. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... and/or thrombocytopenia who may have required red blood cell or platelet transfusions. The overall response rate was ...

    Research Article last updated 06/23/2016 - 10:17am.

  2. Transfusion Thresholds, Quality of Life, and Current Approaches in Myelodysplastic Syndromes

    ... Hemoglobin thresholds and triggers for blood transfusions have changed over the years moving from a higher to a lower ... clinical trials are looking for a more liberal approach of red cell transfusion and the effect on quality of life as opposed to the ...

    Research Article last updated 06/23/2016 - 9:55am.

  3. Patient Inspires Workplace Giving

    ... experienced what I now know as petechiae – little red dots all over my body caused by bleeding into the skin due to low ... other patients, we first knew something wasn’t right when blood work from a routine physical showed significantly low blood cell counts. ...

    Patient Chronicle last updated 06/28/2016 - 8:12am.

  4. NHLBI profiles a member of the Foundation’s patient community.

    ... One Woman’s Determination Helped Her Defeat a Devastating Blood Disease Article Source:  ... the spongy tissue inside the bones — from making enough red blood cells, which carry oxygen to the different parts of the body; white ...

    Article last updated 06/13/2016 - 1:51pm.

  5. Personalized medicine for MDS

    ... patients into “lower-risk” disease, where improvement in blood counts is the main goal of therapy, and “higher-risk” disease, where ... 2 years.  -Lenalidomide works best in patients with red blood cell transfusion dependent MDS patients with lower-risk disease ...

    Research Review last updated 05/02/2016 - 9:44am.

  6. Heather Putney’s Trials (and Travels) with Aplastic Anemia

    ... to the gynecologist and a painless bruise led to a complete blood count draw, which showed markedly low platelets and hematocrit . ... Within two months, I was transfusion dependent for both red blood cells and platelets. In June, I was admitted for an allogenic bone ...

    Patient Chronicle last updated 08/15/2016 - 8:42am.

  7. Iron Chelation

    ... Basics Red blood cells contain iron. Each time you get a red blood cell transfusion ...

    Topic section last updated 06/23/2016 - 3:56pm.

  8. Blood Transfusions

    Blood Transfusions A ... involves only certain parts of blood. These might be the red blood cells, platelets or plasma . Rarely is whole blood (red cells, ... clinics, or even the patient’s home. Red blood cell transfusions can take up to four hours. Transfusions of other blood ...

    Topic section last updated 03/29/2016 - 7:17pm.

  9. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... doses of chemotherapy before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may ... and AAAB guidelines DONOR: Donor and intended recipient red cell type and compatibility will be determined DONOR: Donors will be ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  10. Blood Transfusions: Everything You Need To Know

    ... Blood transfusions are a safe and common procedure that are used to treat blood ... whole blood (with plasma ), and sometimes as packed red blood cells? What does it mean for a patient to be alloimmunized? Is ...

    LMS Item last updated 06/10/2016 - 1:24pm.