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  1. Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

    ... AML. Patients unwilling or unable to comply with the protocol . Patients receiving concomitant treatment with strong CYP3A4 ...

    Clinical Trial last updated 05/23/2016 - 3:37pm.

  2. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... Currently enrolled in another investigational therapy protocol Participants with presence of other active malignancy within ... research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  3. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... informed consent or unable to comply with the treatment protocol including appropriate supportive care , follow-up, and ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  4. 2016 Research Grant Guidelines

    ... has on file: A complete copy of the research protocol approved by the Institutional Review Board with oversight on human ...

    Page last updated 12/09/2015 - 1:50pm.

  5. Coordinated Care: MDS Research and Treatment Centers and Community Hematologists Work Together for Complete Patient Care

    ... text? Even though there is no formal protocol or model for coordinated care, it can be different in other ...

    Interview last updated 07/23/2012 - 4:56pm.

  6. Aplastic Anemia Clinical Trial at the NIH

    ... patient recruitment. If patients don’t agree to be “on protocol”, or if only a few enroll, clinical trials fail or take years to ...

    Research Review last updated 05/02/2016 - 9:26am.

  7. Dose-Escalation Study of FT-2102 as a Single Agent and in Combination With Azacitidine in Patients With AML or MDS With an IDH1 Mutation

    ... as 50 mg or 150 mg capsules and will be administered per the protocol defined frequency and dose level Drug: Azacitidine azacitidine will ...

    Clinical Trial last updated 04/29/2016 - 1:06pm.

  8. Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed/Refractory Acute Leukemia or High-Risk MDS

    ... 20 mg or 100 mg capsules and will be administered per the protocol defined frequency and dose level Other Name: FT1101 ...

    Clinical Trial last updated 04/28/2016 - 9:55am.

  9. Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

    ... 200 cGy (or escalated to 300 cGy, 400 cGy, or 450 cGy per protocol statistical section) Other Names: TOTAL BODY IRRADIATION Whole-Body ...

    Clinical Trial last updated 04/28/2016 - 12:13pm.