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  1. A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib

    ... be able to adhere to the study visit schedule and other protocol requirements Must be able to provide adequate bone marrow ...

    Clinical Trial last updated 06/06/2016 - 2:32pm.

  2. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... Currently enrolled in another investigational therapy protocol Participants with presence of other active malignancy within ... research participant to understand the basic elements of the protocol and/or the risks/benefits of participating in this phase I study ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  3. Lenalidomide and Rituximab in Subjects With Previously Untreated Indolent Non-Hodgkin's Lymphoma

    ... Able to adhere to the study visit schedule and other protocol requirements. Previously untreated, histologically confirmed ...

    Clinical Trial last updated 06/06/2016 - 10:17am.

  4. Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

    ... by cardiology or pulmonary prior to enrollment on this protocol Serum creatinine =<1.5 mg/dL or creatinine clearance > 50 ... some patients with minor deviations may be accepted on protocol after discussion with the principal investigator (PI) Serum ...

    Clinical Trial last updated 05/23/2016 - 2:06pm.

  5. Clinical Trial Basics

    ... research is done according to a detailed plan known as a protocol . The protocol is carefully designed to safeguard the participants’ health and answer specific research questions. A protocol describes the following: Who is eligible to participate in ...

    Page last updated 03/29/2016 - 7:29pm.

  6. Transplants With Unlicensed Preserved Cord Blood

    ... if the transplant will occur under an IND research protocol . These units are in current and future inventory at domestic and ... Indications. This study is an access and distribution protocol conducted by the National Marrow Donor Program (NMDP) for unlicensed ...

    Clinical Trial last updated 04/27/2016 - 3:20pm.

  7. SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)

    ... is able to adhere to the study visit schedule and other protocol requirements, including follow-up for response assessments The ...

    Clinical Trial last updated 06/06/2016 - 2:11pm.

  8. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... considers that HCT on the high-intensity arms of protocol is contraindicated for that patient the patient may be considered for treatment on the lower intensity arm of the protocol or excluded from the protocol; patients with Gilbert's syndrome and no ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  9. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... allogeneic peripheral blood stem cell (PBSC) transplant protocol (03-H-0170) for patients with severe sickle cell disease (SCD) and ... (and reduce the transplant failure rate) in this new protocol, we will continue our nonmyeloablative approach in the patients with ...

    Clinical Trial last updated 04/28/2016 - 9:09am.

  10. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... has elapsed between last treatment and enrollment on protocol Eastern Cooperative Oncology Group (ECOG) performance status ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.