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  1. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... Inclusion Criteria:  Note: protocol eligible patients according to the criteria outlined below will ... If 200 cGy of prior TBI then only 400 CGy of TBI on this protocol is permitted. Uncontrolled viral, bacteria or fungal infection ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  2. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... contributed to this high incidence of cGVHD. In this protocol , we attempt to prevent graft failure and to reduce the incidence ... using the identical conditioning regimen utilized in protocol 99-H-0050. Using the Miltenyi CliniMACs system, recipients will ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  3. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... illness and the investigational nature of the study protocol (including foreseeable risks and possible side effects), and must ... Human Services. Approval for the use of this treatment protocol by the individual institution's Human Rights Committee must be ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.

  4. Clinical Trial Basics

    ... research is done according to a detailed plan known as a protocol . The protocol is carefully designed to safeguard the participants’ health and answer specific research questions. A protocol describes the following: Who is eligible to participate in the ...

    Page last updated 03/29/2016 - 7:29pm.

  5. Azacitidine-lenalidomide (ViLen) combination yields a high response rate in higher risk myelodysplastic syndromes (MDS)-ViLen-01 protocol

    ...

    Research Article last updated 09/13/2016 - 2:47pm.

  6. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... for autologous transplant or a higher priority protocol . Myelodysplastic syndrome (MDS): RA/RCMD with high risk ... evolved from MDS, who are not eligible for a higher priority protocol. Chronic myelomonocytic leukemia: CMML-1 and CMML-2, advanced ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  7. Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

    ... Patient must have received crenolanib on this protocol prior to HSCT to continue on to maintenance. Patient must be ... (HSCT). Response to previous treatment on this protocol: at least resistant disease with clinical benefit or better response. ...

    Clinical Trial last updated 06/06/2016 - 10:04am.

  8. Eltrombopag Added to IST Yields Encouraging Results

    ... anemia? One new study is already underway – a protocol to try to prevent relapse in patients who remain on cyclosporine ...

    Interview last updated 05/24/2017 - 7:44am.

  9. Youmna Kfoury, PhD

    ... in Tianjin and established an agreed upon standardized protocol   for banking, analyzing and sorting BM from MDS patients. As a ... 3-    Optimization of low input RNA sequencing protocol Given the small volume of BM aspirate that we get from ...

    Grant Recipient last updated 12/15/2016 - 12:56pm.

  10. A Phase I Study to Assess the Safety APL-2 as an Add-On to Standard of Care in Subjects With PNH

    ... pregnancy test at screening and must agree to use protocol defined methods of contraception for the duration of the study ... female partners of child bearing potential must agree to use protocol defined methods of contraception (see below) and agree to refrain from ...

    Clinical Trial last updated 08/24/2016 - 11:15am.