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  1. A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

    ... . Eltrombopag has been shown to increase platelet counts in patients with thrombocytopenia from various etiologies ( ... intermediate-2 or high risk MDS by IPSS, and baseline platelet count of <75 Giga (10^9) per liter (Gi/L) will only be enrolled. This ...

    Clinical Trial last updated 04/27/2016 - 1:28pm.

  2. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... and at least one of the following features: Platelet count <20 x 109/L or platelet transfusion dependence* ANC <1000 x 109/L Hgb <8 gm/dl or ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  3. Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

    ... pregnancy to 0.92 units per month during pregnancy. Platelet transfusions were given in 16 pregnancies. In 54% of pregnancies ...

    Research Article last updated 10/12/2015 - 10:05am.

  4. Growth Factors

    ... Platelet Growth Factor Platelet growth factor is called thrombopoietin. It is a ...

    Topic section last updated 04/06/2016 - 12:37pm.

  5. Thrombopoiesis-stimulating agents and myelodysplastic syndromes

    ... to reduce bleeding events, decrease dependency on platelet transfusions and extend exposure to disease-modifying therapies. ...

    Research Article last updated 03/04/2015 - 10:20am.

  6. Special Issues for People with Aplastic Anemia

    ... to: Get a red blood cell count and a platelet count Get transfusions if necessary Ask your doctor if ... of problems during pregnancy if: You have a low platelet count. You also have PNH . If you have had aplastic ...

    Page last updated 06/08/2017 - 2:07pm.

  7. Current and future management options for myelodysplastic syndromes.

    ... supportive care measures consisting of blood and platelet transfusions, haematopoietic growth factors and antimicrobials ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Acute Myeloid Leukemia (AML)

    ... from anemia and a risk of bleeding from a low platelet count. There is also an increased risk of infection, since ... bleeding and easy bruising caused by a very low platelet count called thrombocytopenia , which may also include the ...

    Topic section last updated 07/07/2016 - 3:15pm.

  9. Special Precautions

    ... clots Can cause serious bleeding in people with a low platelet count May require platelet transfusions before surgery. If you do have surgery, it is a ...

    Topic section last updated 09/08/2017 - 12:34pm.

  10. Eltrombopag Added to IST Yields Encouraging Results

    ... first, we had only hoped eltrombopag would improve the platelet transfusion frequency in patients who had not adequately responded ... To our surprise, we observed not only an improvement in platelet counts but also noticed recovering red and white blood cells numbers. ...

    Interview last updated 05/24/2017 - 7:44am.