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  1. Eltrombopag and improved hematopoiesis in refractory aplastic anemia

    ... minimal toxic effects. Nine patients no longer needed platelet transfusions (median increase in platelet count, 44,000 per cubic millimeter). Six patients had improved ...

    Research Article last updated 07/31/2012 - 2:24pm.

  2. Jeff Paccione: “Don’t worry, I’m not going anywhere.”

    ... office, he said “Your red and white blood cells and platelet levels are critically low. I am stunned that you are still ... collapsed. You must go to the hospital now to get blood and platelet transfusions.” Days later, after myriad diagnostic tests, blood and ...

    Patient Chronicle last updated 05/23/2017 - 10:40am.

  3. Th17 immune responses contribute to the pathophysiology of aplastic anemia.

    ... the severity of BM failure with significantly higher platelet (P < .01) and total BM cell (P < .05) counts at day 10. ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Impact of age on outcomes after bone marrow transplantation for acquired aplastic anemia using HLA-matched sibling donors.

    ... patients aged over 40 years had a lower likelihood of platelet recovery compared to patients aged less than 20 years (OR 0.45, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Types of Blood Transfusions

    ... Red blood cell transfusion Platelet transfusion More on Transfusions What is a Blood ... blood transfusions than any other part of the blood. Platelet Transfusions Platelets are bits of cells in the blood that help ...

    Page last updated 10/31/2014 - 2:34pm.

  6. Phase I study of oral azacitidine in myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia

    ... complete remission, hematologic improvement, or RBC or platelet transfusion independence) was 35% in previously treated patients ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... of IST; the use of specific hemoglobin and platelet levels as triggers for transfusion support; the use of ...

    Research Article last updated 12/17/2013 - 8:30am.

  8. A Phase 1 Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate 1 Risk Myelodysplastic Syndromes

    ... achieved transfusion independence (TI) and 5 of 7 platelet TD patients achieved TI. Conclusions: ARRY-614 was well tolerated ...

    Research Article last updated 01/20/2015 - 1:07pm.

  9. A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

    ... . Eltrombopag has been shown to increase platelet counts in patients with thrombocytopenia from various etiologies ( ... intermediate-2 or high risk MDS by IPSS, and baseline platelet count of <75 Giga (10^9) per liter (Gi/L) will only be enrolled. This ...

    Clinical Trial last updated 04/27/2016 - 1:28pm.

  10. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... and at least one of the following features: Platelet count <20 x 109/L or platelet transfusion dependence* ANC <1000 x 109/L Hgb <8 gm/dl or ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.