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  1. SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution

    ... were closely associated with older age, higher platelet counts, lower lactate dehydrogenase levels, good-risk ...

    Research Article last updated 04/23/2014 - 11:18am.

  2. IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution.

    ... mutations were closely associated with older age, higher platelet counts, and mutations of DNMT3A (36.4% vs. 8.7%, P<0.001), ASXL1 ...

    Research Article last updated 10/22/2013 - 12:48pm.

  3. Retrospective Analysis of Prognostic Factors Associated With Response and Overall Survival by Baseline Marrow Blast Percentage in Patients With Myelodysplastic Syndromes Treated With Decitabine.

    ... vs. 16% high-risk patients), and lower median baseline platelet count (62.3 vs. 112.7 × 103/μL) vs. patients with MDS (n = 157), ...

    Research Article last updated 06/28/2013 - 1:20pm.

  4. Thrombosis in paroxysmal nocturnal hemoglobinuria.

    ... will be discussed. Mechanisms explored include platelet activation, toxicity of free hemoglobin , nitric oxide ...

    Research Article last updated 05/14/2013 - 3:29pm.

  5. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... UD). All patients showed neutrophil and platelet engraftment . Cumulative incidence of acute (grade 2 or ...

    Research Article last updated 05/14/2013 - 1:00pm.

  6. Prognosis of acute myeloid leukemia transformed from myelodysplastic syndromes: A multicenter retrospective study

    ... time was 142 days. In patients treated with BSC, platelet count alone was an independent prognostic factor. In younger ...

    Research Article last updated 04/02/2013 - 7:59am.

  7. Prognostic Factors Associated With Disease Progression and Overall Survival in Patients With Myelodysplastic Syndromes Treated With Decitabine.

    ... to AML. A hemoglobin value at least 10 g/dL, platelet count at least 50 × 10(3)/μL, and lack of chromosome 5 or 7 ...

    Research Article last updated 01/02/2013 - 2:53pm.

  8. Cotransplantation of allogeneic mesenchymal and hematopoietic stem cells in children with aplastic anemia

    ... × 10(6)/kg). The mean time for neutrophil and platelet recovery was 12.3 and 13.8 days, respectively. Acute GvHD grade I ...

    Research Article last updated 07/30/2012 - 1:18pm.

  9. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... = .01). However, neutrophil recovery at day -28, platelet recovery at day -100, acute GVHD, chronic GVHD, and overall ...

    Research Article last updated 06/15/2012 - 2:55pm.

  10. Asymptomatic cerebral bleeds in patients with aplastic anemia.

    ... gm/dl), white cell count 2,320/μl (800-7,000/μl), and platelet count 11,500/μl (7000-45,000/μl). Three patients were detected ...

    Research Article last updated 06/15/2012 - 2:46pm.