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  1. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 11/02/2016 - 10:39am.

  2. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... who may have required red blood cell or platelet transfusions. The overall response rate was 40 %, including ... include overall survival, hematologic response including platelet response and erythroid response, RBC transfusion independence ...

    Research Article last updated 06/23/2016 - 10:17am.

  3. Patient Inspires Workplace Giving

    ... over my body caused by bleeding into the skin due to low platelet counts. After I got to know what the symptoms of aplastic ...

    Patient Chronicle last updated 06/28/2016 - 8:12am.

  4. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... RBC-transfusion dependence (p = 0.0033; HR 2.67L), platelet transfusion dependence (p = 0.0071; HR 3.321), hemoglobin ... concentration higher than 1000 ng/L (p = 0.0023; HR = 2.94), platelet count lower than 10 G/L (p = 0.0081 HR = 5.04), acute leukemia ...

    Research Article last updated 10/06/2016 - 1:01pm.

  5. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 08/15/2016 - 9:10am.

  6. Strong results for SAA patients at Johns Hopkins

    ... of the patients' red and white blood cell and platelet counts had returned to normal levels without the need for blood ...

    Article last updated 02/07/2017 - 11:05am.

  7. Fighting PNH While Helping PNH Patients

    ... again -- I was away from it for about a year. My platelet count had not been that bad… it was the hemolysis , ...

    Patient Chronicle last updated 11/21/2016 - 12:47pm.

  8. Thrombocytopenia in patients with myelodysplastic syndromes.

    ... for increased risk of bleeding and delay of therapy. Platelet transfusions, although effective in increasing platelet counts, are limited by supply, are associated with risks, and result ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes

    ... or partial remission, red blood cell [RBC] or platelet transfusion independence [TI], or hematologic improvement, (IWG ...

    Research Article last updated 12/09/2015 - 8:56am.

  10. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... time of 16 days (range 9-25 days). The median time of platelet engraftment was 22 days (range 9-95 days) in 16 patients. The ...

    Research Article last updated 09/04/2014 - 11:22am.