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  1. Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

    ... Three of 4 patients had an improvement in their platelet count, and 3 of 3 had major improvement in abdominal pain/discomfort. The one patient whose platelet count did not respond had developed marrow failure, and she did well ...

    Research Article last updated 04/17/2014 - 1:34pm.

  2. The Effect of Decitabine Dose Modification and Myelosuppression on Response and Survival in Patients With Myelodysplastic Syndromes

    ... Cox regression analyses of red blood cell or platelet dependence, myelosuppression, dose modification, cycle delay or ... reduction, and survival effects. In 182 patients, baseline platelet dependence was a predictor for dose modification, reduction, or ...

    Research Article last updated 06/02/2014 - 11:03am.

  3. Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes

    ... patients with transfusion-dependent anemia or platelet counts <50 × 109 /L or a significant clinical hemorrhage requiring platelet transfusion or ANC <1 × 109 /L were eligible, with most of our ...

    Research Article last updated 05/22/2014 - 10:33am.

  4. Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations.

    ... Low karyotype complexity (by CC) and a high baseline platelet count (>280 × 109 /l) were associated with the achievement of ... important predictor for lenalidomide treatment failure was a platelet count <280 × 109 /l (Odds Ratio = 6·17, P = 0·040). This study ...

    Research Article last updated 07/29/2014 - 8:58am.

  5. The dysfunction of platelets in paroxysmal nocturnal hemoglobinuria

    ... of thrombosis in PNH remains unclear. To explore this, platelet function and serum complement activity were investigated in 14 ... assay (ELISA), and the levels of C5b-9, CD61 and CD62p on platelet membranes were determined by flow cytometry . Clinical ...

    Research Article last updated 11/02/2016 - 10:37am.

  6. Transplant saves student who thought she had mono

    ... to get home for the holidays. I chalked the mono and low platelet count up to being super-stressed, and made an appointment to see ...

    Article last updated 03/06/2017 - 2:37pm.

  7. Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

    ... eltrombopag olamine works in improving the recovery of platelet counts in older patients with acute myeloid leukemia undergoing ... first treatment given for a disease) chemotherapy . Platelet counts recover more slowly in older patients, leading to risk of ...

    Clinical Trial last updated 05/03/2016 - 11:56am.

  8. Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results

    ... engraftment was 12 days (range 8-21 days) and for platelet engraftment was 19 days (range 8-154 days). The incidence was ...

    Research Article last updated 02/01/2017 - 12:30pm.

  9. Horse ATG Saves Young Equestrian

    ... Liviya immediately began receiving blood and platelet transfusions, of course. We learned that Liviya’s older brother ...

    Patient Chronicle last updated 01/04/2017 - 3:06pm.

  10. Efficacy, safety, and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes

    ... transfusion independence and 7 of 18 attained platelet transfusion independence. Most common grade 3-4 treatment-emergent ...

    Research Article last updated 02/03/2017 - 10:05am.