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  1. EHA S826: Eltrombopag Added to Standard Immunosuppression as First Treatment in Severe Aplastic Anemia

    ... Eltrombopag (Promacta®) is a treatment that increases platelet counts and decreases bleeding risk. This phase 2 clinical ... at six months. Cohort 1 patients stopped needing platelet transfusions after a median 32 days of treatment. They stopped needing ...

    Research Review last updated 05/02/2016 - 9:10am.

  2. A Phase I Study to Assess the Safety APL-2 as an Add-On to Standard of Care in Subjects with PNH

    ... within 12 months prior to screening Platelet count of > 30,000/mm3 Absolute neutrophil ...

    Clinical Trial last updated 07/19/2016 - 12:46pm.

  3. Pure Red Cell Aplasia (PRCA)

    ... cell count. The amounts of white blood cells and platelet remain normal. Transient or Acute Self-limited PRCA:   ...

    Topic section last updated 07/07/2016 - 3:14pm.

  4. Clinical Utility of Lenalidomide in the Treatment of Myelodysplastic Syndromes

    ... are near this del(5q) region include those that affect platelet production. Furthermore, the entity of 5q-syndrome (which is ... Phase III study is underway now. A study combining platelet growth factors and lenalidomide preliminarily demonstrated decreased ...

    Research Review last updated 05/02/2016 - 9:12am.

  5. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... to determine the time to neutrophil and platelet engraftment , to determine the time to immune ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.

  6. New York Blood Center National Cord Blood Program

    ... is obtained to assess cord blood myeloid and platelet engraftment , transplant related mortality, overall ...

    Clinical Trial last updated 06/13/2016 - 1:43pm.

  7. MDS - Treatment (OLD)

    ... A transfusion for red blood cells takes 2 to 4 hours. A platelet transfusion takes 30 to 60 minutes. As with any medical ... donated stem cells engraft, you may need blood and/or platelet transfusions to keep your blood cells numbers up. During this time ...

    Topic section last updated 03/10/2016 - 11:01pm.

  8. REVERSE 1 INCB 18424-271

    ... supplementation is allowed. Evidence of platelet engraftment (ie, platelets ≥ 20 × 10^9/L) ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  9. Dr. Vivienne Rebel reports on a study of the relationship between gene mutations and overall survival after stem cell transplant

    ... Clinical parameters, such as blast counts and platelet counts, are important indicators of the severity of MDS and thus ...

    Research Review last updated 05/02/2016 - 9:16am.

  10. Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

    ... by a requirement for red blood cell and platelet transfusions. Three different preparative regimens are included ...

    Clinical Trial last updated 04/25/2016 - 10:59am.