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  1. Romiplostim monotherapy in thrombocytopenic patients with myelodysplastic syndromes: long-term safety and efficacy

    ... Romiplostim can improve platelet counts in about 50% of patients with low- or intermediate 1-risk ... of romiplostim in 60 patients with lower risk MDS and platelet counts ≤50 × 109 /l. The primary endpoint was adverse event (AE) ...

    Research Article last updated 07/11/2017 - 10:22am.

  2. Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial.

    ... and severe thrombocytopenia. Patients with a stable platelet count of lower than 30 × 109 platelets per L, aged at least ... endpoints were the proportion of patients achieving a platelet response within 24 weeks and safety. The interim analysis presented ...

    Research Article last updated 02/21/2017 - 9:49am.

  3. What is a complete blood count test (CBC)?

    ... This number is about 3 times the hemoglobin. Platelet count measures the number of platelets in a given volume of ...

    FAQ last updated 01/04/2018 - 12:09pm.

  4. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... this approach. Patients may require frequent blood and platelet transfusion support which is expensive and inconvenient. ... complications still occur despite prophylactic platelet transfusion. Thrombopoietin (TPO) mimetics, such as romiplostim and ...

    Research Article last updated 06/20/2013 - 10:13am.

  5. Outcomes and healthcare utilization in children and young adults with aplastic anemia: A multiinstitutional analysis

    ... interval [CI] 0.6-2.58, P = 0.567), while every platelet transfusion was associated with higher mortality (OR 1.37, 95% CI ...

    Research Article last updated 07/18/2017 - 10:32am.

  6. What are the treatments for aplastic anemia?

    ... for aplastic anemia. This drug is a platelet growth factor , but seems to stimulate growth of red cells ...

    FAQ last updated 01/04/2018 - 12:29pm.

  7. Altered immunophenotypic features of peripheral blood platelets in myelodysplastic syndromes.

    ... cytometry for the detection of megakaryocytic and platelet dysplasia has not yet been investigated. The aim of this pilot ... by flow cytometry the diagnostic and prognostic value of platelet dysplasia in myelodysplastic syndromes. DESIGN AND METHODS: We ...

    Research Article last updated 06/15/2012 - 2:25pm.

  8. Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial

    Journal Title:  Leukemia Primary Author:  Platzbecker U Author(s):  Platzbeck...

    Research Article last updated 09/24/2014 - 11:12am.

  9. Under-recognition of Platelet dysfunction in Myelodysplastic Syndromes: are we only seeing the tip of the iceberg?

    Journal Title:  Leuk Lymphoma Primary Author:  Burbury KL Author(s):  Burbury...

    Research Article last updated 10/01/2012 - 10:01am.

  10. SAA patient finds unrelated donor match in 2 weeks

    ... through the journey alone. Blood, bone marrow and platelet drives have drawn overwhelming numbers, and a GoFundMe account ...

    Article last updated 03/21/2017 - 11:19am.