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  1. A Phase I Study to Assess the Safety APL-2 as an Add-On to Standard of Care in Subjects with PNH

    ... Hb < 10 g/dL at screening OR have received at least one transfusion within 12 months prior to screening Platelet count of > 30,000/mm3 Absolute neutrophil ...

    Clinical Trial last updated 07/19/2016 - 12:46pm.

  2. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... cytopenia (s), and/or red blood cell or platelet transfusion dependence, or patients with aplasia, or patients with excess ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  3. Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

    ... to a single course of ATG (non-robust responders), even when transfusion-independence is achieved, predicts a worse prognosis than when ... (TPO) is the principal endogenous regulator of platelet production. In addition, TPO also has stimulatory effects on more ...

    Clinical Trial last updated 04/25/2016 - 2:47pm.

  4. Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery

    ... ≥ 1.5 × 109; Platelets ≥ 100 × 109 (without platelet transfusion ); Hemoglobin ≥ 9.0 g/dL(with or without red ...

    Clinical Trial last updated 04/28/2016 - 1:57pm.

  5. Blood Transfusions: Everything You Need To Know

    ... Dr. Daria Babushok will begin by walking you through the transfusion process and the different types of transfusions. She will then ... The difference between red blood cell , platelet and plasma transfusions.  Possible side-effects you may ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. Blood Transfusions: Everything You Need To Know

    ... 2016, Dr. Daria Babushok begins by walking you through the transfusion process and the different types of transfusions. She then explains ... The difference between red blood cell , platelet and plasma transfusions.  Possible side-effects you may ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  7. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... from infection or bleeding, and they require regular platelet and/or red blood cell transfusions, which are expensive ... 7 eventually became tri-lineage responders. Nine became transfusion-independent for platelets (median increase in platelet count ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  8. “Mom, it’s too late. I’m dying.”

    ... Within an hour, he was getting blood transfusions and platelet transfusions. The emergency room doctors told me that they had ... his blood counts to come back up. Jake continued to be transfusion dependent, and we returned to Boston for another bone marrow ...

    Patient Chronicle last updated 04/26/2016 - 11:43am.

  9. Infections in myelodysplastic syndromes: a review

    ... and liver disease and particularly those with greater transfusion needs are most vulnerable to infections. Available data from two ... requirements prior to starting azacytidine therapy and platelet counts < 20,000/μl to be significantly associated with occurrence ...

    Research Review last updated 05/02/2016 - 9:28am.

  10. ASH 2012 - Reviewing MDS Progress from Research and Clinical Perspectives

    ... purpura (ITP). Patients with ITP have a low platelet count, not because of a bone marrow problem, but due to an ... earlier studied in patients with MDS who also have a low platelet count and in the largest study, it was found that romiplostin ... treated with romiplostin, based on prior platelet transfusion needs and blood levels of the hormone TPO. So just ...

    Interview last updated 02/07/2013 - 1:28pm.