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  1. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... was 25 (range, 2 to 58) days, and to last platelet transfusion to keep platelets counts over 50 × 103/mm3 was 27.5 ...

    Research Article last updated 01/24/2017 - 10:04am.

  2. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... change in hemoglobin (Hb) level, the withdrawal of transfusion and corticosteroids, the change of renal function, and overall ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 11/02/2016 - 10:39am.

  3. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... this approach. Patients may require frequent blood and platelet transfusion support which is expensive and inconvenient. Life-threatening ...

    Research Article last updated 06/20/2013 - 10:13am.

  4. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... who may have required red blood cell or platelet transfusions. The overall response rate was 40 %, including hematologic improvement in 28 % of patients and RBC transfusion independence sustained for 56 days in 47 % of patients with ...

    Research Article last updated 06/23/2016 - 10:17am.

  5. Left main crossover stenting in a patient with severe thrombocytopenia due to aplastic anemia

    ... 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia ( platelet 11 × 103/μL, hemoglobin 6.4 g/dL). Refractory ...

    Research Article last updated 12/09/2016 - 2:08pm.

  6. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... change in hemoglobin (Hb) level, the withdrawal of transfusion and corticosteroids, the change of renal function, and overall ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 08/15/2016 - 9:10am.

  7. Blood Transfusions

    ... A transfusion usually involves only certain parts of blood. These might be the ... transfusions include red blood cell transfusion and platelet transfusion . Red Blood Cell Transfusions Red blood cells ...

    Topic section last updated 03/29/2016 - 7:17pm.

  8. Patient Inspires Workplace Giving

    ... over my body caused by bleeding into the skin due to low platelet counts. After I got to know what the symptoms of aplastic ... tell me to get to a hospital emergency room for a blood transfusion right away. After my first blood transfusion, I saw a ...

    Patient Chronicle last updated 06/28/2016 - 8:12am.

  9. Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes

    ... System and only those low/intermediate-1 patients with transfusion-dependent anemia or platelet counts <50 × 109 /L or a significant clinical hemorrhage ...

    Research Article last updated 05/22/2014 - 10:33am.

  10. Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes

    ... or partial remission, red blood cell [RBC] or platelet transfusion independence [TI], or hematologic improvement, (IWG 2006) was ...

    Research Article last updated 12/09/2015 - 8:56am.