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  1. Blood Transfusions

    Blood Transfusions A transfusion usually involves only certain parts of blood. These might be the ... transfusions include red blood cell transfusion and platelet transfusion . Red Blood Cell Transfusions Red blood cells ...

    Topic section last updated 03/29/2016 - 7:17pm.

  2. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... who may have required red blood cell or platelet transfusions. The overall response rate was 40 %, including hematologic improvement in 28 % of patients and RBC transfusion independence sustained for 56 days in 47 % of patients with ...

    Research Article last updated 06/23/2016 - 10:17am.

  3. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... change in hemoglobin (Hb) level, the withdrawal of transfusion and corticosteroids, the change of renal function, and overall ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 08/15/2016 - 9:10am.

  4. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... this approach. Patients may require frequent blood and platelet transfusion support which is expensive and inconvenient. Life-threatening ...

    Research Article last updated 06/20/2013 - 10:13am.

  5. Patient Inspires Workplace Giving

    ... over my body caused by bleeding into the skin due to low platelet counts. After I got to know what the symptoms of aplastic ... tell me to get to a hospital emergency room for a blood transfusion right away. After my first blood transfusion, I saw a ...

    Patient Chronicle last updated 06/28/2016 - 8:12am.

  6. Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes

    ... System and only those low/intermediate-1 patients with transfusion-dependent anemia or platelet counts <50 × 109 /L or a significant clinical hemorrhage ...

    Research Article last updated 05/22/2014 - 10:33am.

  7. Eltrombopag Added to IST Yields Encouraging Results

    ... first, we had only hoped eltrombopag would improve the platelet transfusion frequency in patients who had not adequately responded to ...

    Interview last updated 05/24/2017 - 7:44am.

  8. Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes

    ... or partial remission, red blood cell [RBC] or platelet transfusion independence [TI], or hematologic improvement, (IWG 2006) was ...

    Research Article last updated 12/09/2015 - 8:56am.

  9. Brittany Springer – Aplastic Anemia Patient “Just Focused on Beating It”

    ... she thought I might have leukemia. She told me I needed a transfusion (my platelet count was 56). I was so upset I could not speak. I asked her to ...

    Patient Chronicle last updated 04/29/2016 - 3:29pm.

  10. Jeff Paccione: “Don’t worry, I’m not going anywhere.”

    ... office, he said “Your red and white blood cells and platelet levels are critically low. I am stunned that you are still ... waiting room before Jeff received platelets and a blood transfusion , he leaned over to me and quietly assured me, “Don’t worry, ...

    Patient Chronicle last updated 05/23/2017 - 10:40am.