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  1. ASCO Updates Platelet Transfusion Guideline Prophylaxis unnecessary for adults undergoing HSCT

    ... stem-cell transplants (HSCT) may safely delay platelet infusion until the first sign of bleeding, as opposed to ... infusion, according to an updated guideline for platelet transfusion in patients with cancer. The recommendation, which applies ...

    Research Article last updated 12/06/2017 - 11:23am.

  2. Jill Minden’s Encounter with Aplastic Anemia

    ... turned into hospitals, weekly red blood cell and platelet transfusions, and lots of fear. I was treated at Barnes Jewish ... I responded better, and my counts were able to stay above transfusion level for a little over a year. T.J. and I got married in 2009 and ...

    Patient Chronicle last updated 09/05/2017 - 10:57am.

  3. Outcomes and healthcare utilization in children and young adults with aplastic anemia: A multiinstitutional analysis

    ... interval [CI] 0.6-2.58, P = 0.567), while every platelet transfusion was associated with higher mortality (OR 1.37, 95% CI ...

    Research Article last updated 07/18/2017 - 10:32am.

  4. Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

    ... levels and limited red blood cell transfusion history can predict response to erythropoiesis-stimulating agents ... between endogenous thrombopoietin (THPO) levels and platelet response to romiplostim is unknown. Variables including baseline ...

    Research Article last updated 08/04/2014 - 8:33am.

  5. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... are the only treatment option for about 40% of patients. Transfusion-dependent patients develop secondary iron overload . The ... RBC-transfusion dependence (p = 0.0033; HR 2.67L), platelet transfusion dependence (p = 0.0071; HR 3.321), hemoglobin ...

    Research Article last updated 10/06/2016 - 1:01pm.

  6. Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial.

    ... and severe thrombocytopenia. Patients with a stable platelet count of lower than 30 × 109 platelets per L, aged at least ... need for early trial termination. Duration of platelet transfusion independence, duration of response, overall survival, ...

    Research Article last updated 02/21/2017 - 9:49am.

  7. Efficacy, safety, and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes

    ... hematologic improvement, 12 of 32 patients attained RBC transfusion independence and 7 of 18 attained platelet transfusion independence. Most common grade 3-4 treatment-emergent ...

    Research Article last updated 02/03/2017 - 10:05am.

  8. Denise Beauchemin - My Life is Making a Difference

    ... began to respond. By the end of May, I had my last red cell transfusion and by early June had my last platelet transfusion . One side effect of treatment with cyclosporine is ...

    Patient Chronicle last updated 04/12/2017 - 7:12am.

  9. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... was 25 (range, 2 to 58) days, and to last platelet transfusion to keep platelets counts over 50 × 103/mm3 was 27.5 ...

    Research Article last updated 01/24/2017 - 10:04am.

  10. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... change in hemoglobin (Hb) level, the withdrawal of transfusion and corticosteroids, the change of renal function, and overall ... were observed, especially in patients with platelet count ≥150 × 109/L. Approximately 97 % of patients showed ...

    Research Article last updated 11/02/2016 - 10:39am.