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  1. A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MEDALIST)

    ... THE EFFICACY AND SAFETY OF LUSPATERCEPT (ACE-536) VERSUS PLACEBO FOR THE TREATMENT OF ANEMIA DUE TO IPSS-R VERY LOW, LOW, OR ... Drug: Luspatercept Other Name: ACE-536 Other: Placebo ...

    Clinical Trial last updated 04/21/2016 - 1:16pm.

  2. Clinical Trials: What Are Phases, and What Happens in Each One?

    ... everyone in the trial gets the drug. There is often no placebo arm of this trial. This is called a ‘single arm’ study. However ... newer Phase 2 designs do have a control arm, whether it is a placebo or another therapy – and this is known as a two-arm study. By ...

    Interview last updated 11/16/2015 - 8:32am.

  3. Effectiveness of lenalidomide in patients over 75 vs. patients under 75 with RBC transfusion-dependent low/int-1-risk MDS and del5q

    ... MDS was recently confirmed in MDS-004, a randomized, placebo -controlled trial, which again demonstrated that lenalidomide ...

    Research Review last updated 05/02/2016 - 9:32am.

  4. Types of Research Articles Part I

    ... are randomly assigned to one or more treatments or to a placebo . Also, the patients and the physicians treating them don’t know whether the patient is getting an active treatment or a placebo. Use clinical trial reports to: Find out about a rigorous ...

    Page last updated 08/20/2015 - 12:50pm.

  5. Dr. Vivienne Rebel reviews a recent study about p53 protein levels as a prognostic factor in MDS

    ... trial, for which they received lenalidomide or a placebo .  P53 staining was performed on samples prior to any treatment and ...

    Research Review last updated 05/02/2016 - 9:17am.

  6. More Information

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    Page last updated 01/20/2015 - 4:59pm.

  7. More Information

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    Page last updated 01/20/2015 - 4:47pm.

  8. Clinical Trials – An Option for Patients and Their Treatment Team to Consider

    ... or an alternative such as an already approved therapy or placebo in its place. A placebo is a treatment that looks just like the experimental treatment but ...

    Page last updated 01/17/2014 - 3:22pm.

  9. Clinical Trial Basics

    ... the new study treatment, the standard treatment, or a placebo . Clinical trials may compare a new medical approach to a standard one that is already available or to a placebo that contains no active ingredients or to no intervention. Some ...

    Page last updated 03/29/2016 - 7:29pm.

  10. From Bench to Bedside: Why Research is Important

    ... treatment, sometimes an inactive substance (called a placebo ) or a different drug currently approved for treatment. Many studies ...

    Page last updated 03/19/2016 - 12:22pm.