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  1. Taming the nausea, vomiting caused by chemo

    ... to treat nausea/vomiting than patients who received a placebo plus the three antiemetic drugs. The investigators believe the ... were randomly assigned to receive olanzapine or a placebo, in combination with the other three drugs, immediately before and for ...

    Article last updated 08/11/2016 - 3:27pm.

  2. Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study

    ... or 5 mg/day (days 1-28; n = 43) on 28-day cycles, or placebo (n = 45). From the placebo and lenalidomide 5 mg groups, 84% and 58% of patients, respectively, ...

    Research Article last updated 07/29/2014 - 12:12pm.

  3. Self-injected PNH therapy on the horizon

    ... most people miss" in the disease is that "there is no placebo response. It doesn't happen" in phase III trials. "We actually have ...

    Article last updated 07/07/2016 - 9:40am.

  4. Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria.

    ... in CKD stage (P < 0.001) compared with baseline and to placebo (P = 0.04). Improvement in renal function was more commonly seen ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS

    ... treatment arms (in the randomized, double-blinded, placebo -controlled Phase 2 portion). ...

    Clinical Trial last updated 06/19/2017 - 2:44pm.

  6. CASCADE (SGN33A-005)

    ... decitabine extends overall survival longer than placebo combined with either azacitidine or decitabine. ...

    Clinical Trial last updated 06/19/2017 - 2:43pm.

  7. MEDALIST Trial

    ... This is a Phase 3, double-blind, randomized, placebo -controlled, multicenter study to determine the efficacy and safety of luspatercept (ACE-536) versus placebo in subjects with anemia due to International Prognostic ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  8. A Combination Study of PF-04449913 and Azacitidine In 1st Line MDS, AML and CMML Patients

    ... This multi center randomized (1:1), double blind, placebo controlled Phase 1b/2 study is designed to compare the safety, ... (PK), and pharmacodynamics (PD) of PF 04449913 or placebo when combined with azacitidine in patients with previously ...

    Clinical Trial last updated 04/27/2016 - 1:20pm.

  9. Interviews with the Experts: Side Effects of PNH Treatment

    ... receiving eculizumab and 9 (21%) patients receiving placebo (inactive ingredient). Among 193 patients with PNH treated with ...

    Interview last updated 08/31/2016 - 8:37am.

  10. Clinical Trials: What Are Phases, and What Happens in Each One?

    ... everyone in the trial gets the drug. There is often no placebo arm of this trial. This is called a ‘single arm’ study. However ... newer Phase 2 designs do have a control arm, whether it is a placebo or another therapy – and this is known as a two-arm study. By ...

    Interview last updated 11/16/2015 - 8:32am.