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  1. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... Purpose:  RATIONALE: A peripheral stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy and radiation ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  2. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... the safety of transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  3. Myelodysplastic syndromes: What do hospitalists need to know?

    ... Myelodysplastic syndromes (MDS) represent a blood disorder characterized by ineffective production of cells leading to low ... kidney function, bleeding, inflammation, and review of a peripheral blood smear.   Ultimately, the diagnosis of MDS requires a ...

    Research Review last updated 05/02/2016 - 9:21am.

  4. Dr. Vivienne Rebel reports on a study of the relationship between gene mutations and overall survival after stem cell transplant

    ... used to identify patient group(s) that would benefit from a blood-stem cell transplantation.  This is an important question since the ...   DNA samples, isolated from bone marrow or peripheral blood cells from 87 patients prior to undergoing a blood- stem ...

    Research Review last updated 05/02/2016 - 9:16am.

  5. RIC Transplant Using Haplo Donors

    ... -mismatched first-degree relatives utilizing PBSC as the stem cell source. The primary objective of the study is to estimate the ... requiring transfusion not responding to therapy; peripheral or BM blast count of <10%; CMML Acute lymphocytic ... Day 4. Other Name: Cytoxan Procedure: peripheral blood stem cell transplant Other Name: HSCT ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  6. Intra-Osseous Co-Transplant of UCB and hMSC

    ... trial studies intra-osseous donor umbilical cord blood and mesenchymal stromal cell co-transplant in treating patients with ... blasts in the marrow and/or ≤ 5% blasts in the peripheral blood Acute lymphoblastic leukemia (ALL) ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  7. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... by an infusion of their donor's bone marrow or blood stem cells . The high-dose chemotherapy drugs and radiation are ... The chemotherapy is followed by an infusion of their donor's peripheral blood stem cells. The objective of the microtransplant is to ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  8. TBI Dose De-escalation for Fanconi Anemia

    ... . 4) If the subject is receiving bone marrow or "peripheral" stem cells (cells collected from the donor's arm via a cell ... stem cells. If the subject is receiving an umbilical cord blood, the lymphocytes will not be removed because the risk of GVHD is not as ...

    Clinical Trial last updated 04/28/2016 - 9:06am.

  9. Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65 (DFCI 10-106)

    ... syndrome (another type of cancer affecting the blood). Dexamethasone is commonly used, either alone, or in combination with ... to comply with an anti-thrombotic treatment regimen Peripheral neuropathy >/= Grade 2 ...

    Clinical Trial last updated 05/23/2016 - 3:45pm.

  10. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... filgrastim neupogen Biological: Peripheral blood stem cell The source of stem cells for all patients will be ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.