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  1. A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation

    ... must be amenable to serial bone marrow biopsies, peripheral blood sampling, and urine sampling during the study. Subjects must have ...

    Clinical Trial last updated 02/22/2017 - 11:21am.

  2. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... malignancies undergoing unrelated donor peripheral blood stem cell transplant . Giving chemotherapy and total-body ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.

  3. Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

    ... graft-versus-host disease (GVHD) after nonmyeloablative peripheral blood stem cell (PBSC) transplant in patients with hematological malignancies. ...

    Clinical Trial last updated 05/03/2016 - 9:44am.

  4. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... This phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients with hematologic ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  5. Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome

    ... For such patients, transplantation using unrelated cord blood (UCB) has been shown to be a reasonable alternative transplant strategy. ... versus host disease compared to mismatched bone marrow or peripheral blood stem cell transplants. The major disadvantage of UCB ...

    Clinical Trial last updated 04/25/2016 - 2:18pm.

  6. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... purpose of this study is to find out whether the addition of blood stem cells from a close family member, when added to two units of umbilical ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  7. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... Giving low doses of chemotherapy before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  8. REVERSE 1 INCB 18424-271

    ... (allo-HSCT) from any donor source using bone marrow , peripheral blood stem cells , or cord blood for hematologic malignancies. ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  9. CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

    ... stem cells (the cells that make all the types of blood cells in the body) are selected (removed) from the donor's peripheral blood stem cells. In doing this, T-cells (a type of blood cell) are ...

    Clinical Trial last updated 04/28/2016 - 8:36am.

  10. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... Our ongoing nonmyeloablative allogeneic peripheral blood stem cell (PBSC) transplant protocol (03-H-0170) for patients ...

    Clinical Trial last updated 04/28/2016 - 9:09am.