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  1. How I treat acquired aplastic anemia

    ... and the consequences of therapy. Recent insights into pathophysiology have practical implications. We review key aspects of ...

    Research Article last updated 07/30/2012 - 2:00pm.

  2. Genetics of myelodysplastic syndromes: new insights

    ... in MDS samples has led to new insights into the pathophysiology of these disorders. Of particular interest is the recent ...

    Research Article last updated 01/09/2012 - 2:04pm.

  3. Immunomodulating drugs in myelodysplastic syndromes

    ... mechanisms that appear to play an important role in the pathophysiology of at least part of the lower-risk myelodysplastic syndrome ...

    Research Article last updated 01/09/2012 - 2:00pm.

  4. Aplastic anemia: immunosuppressive therapy in 2010

    ... by an empty bone marrow; an immune-mediated pathophysiology has been demonstrated by experimental works as well as by ...

    Research Article last updated 11/08/2011 - 7:59am.

  5. Epigenetic regulation in myelodysplastic syndromes: implications for therapy.

    ... that targeting epigenetic mechanisms improves MDS/AML pathophysiology . AREAS COVERED: This review provides an understanding of ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. A closer look at paroxysmal nocturnal hemoglobinuria

    ... This review summarizes current knowledge of the pathophysiology , diagnostic modalities, clinical implications, and ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. The helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes.

    ... data suggest role for dysregulation of TWIST in the pathophysiology of MDS. Conceivably, TWIST or components in the signaling ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders

    ... diseases with a proved or suspected complement-mediated pathophysiology have been considered as candidate for a clinical complement ...

    Research Article last updated 10/02/2012 - 10:00am.

  9. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... which are used to study further etiology and pathophysiology of AA and test new drugs and approaches in treating and ...

    Research Article last updated 11/14/2013 - 11:18am.

  10. Interferon-gamma and tumor necrosis factor-alpha induce an immunoinhibitory molecule, B7-H1, via nuclear factor-kappaB activation in blasts in myelodysplastic syndromes.

    ... together, these findings provide new insight into MDS pathophysiology . IFNgamma and TNFalpha activate NF-kappaB that in turn ...

    Research Article last updated 10/11/2011 - 5:58pm.