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  1. Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise?

    ... recurrent mutations that play a vital role in the pathophysiology of MDS and the impact of these genetic changes on disease ...

    Research Article last updated 09/28/2015 - 9:48am.

  2. Genetics factors associated with myelodysplastic syndromes

    ... recurrent mutations, leading to new insights into the pathophysiology of MDS. The recent recognition that genes involved in the ...

    Research Article last updated 06/03/2015 - 11:30am.

  3. Non-t(6;9) and Non-Inv(3) Balanced Chromosomal Rearrangements Are Associated With Poor Survival Outcomes in Myelodysplastic Syndromes

    ... collected. Direct sequencing for genes relevant in MDS pathophysiology was performed on patients with BCR. Categorical data were ...

    Research Article last updated 06/03/2015 - 8:44am.

  4. Myelodysplastic syndromes

    ... the syndromes are most common in elderly people. The pathophysiology involves cytogenetic changes with or without gene ...

    Research Article last updated 04/16/2014 - 12:04pm.

  5. Iron overload and chelation therapy in myelodysplastic syndromes

    ... in depth analysis of iron overload in MDS patients; its pathophysiology , effect on survival, associated risks and diagnostic ...

    Research Article last updated 03/12/2014 - 10:20am.

  6. Stem cell origin of myelodysplastic syndromes

    ... of multipotent, immature hematopoietic cells in the pathophysiology of this disease. Recent studies using murine models of MDS ...

    Research Article last updated 01/08/2014 - 9:05am.

  7. Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition

    ... to nitric oxide depletion that mediates the pathophysiology of some of the common clinical signs of PNH. Clinical ...

    Research Article last updated 11/05/2013 - 12:37pm.

  8. Thrombosis in paroxysmal nocturnal hemoglobinuria.

    ... review the recent changes in our understanding of the pathophysiology of thrombosis in PNH as well as the treatment of thrombosis ...

    Research Article last updated 05/14/2013 - 3:29pm.

  9. How I treat acquired aplastic anemia

    ... and the consequences of therapy. Recent insights into pathophysiology have practical implications. We review key aspects of ...

    Research Article last updated 07/30/2012 - 2:00pm.

  10. Genetics of myelodysplastic syndromes: new insights

    ... in MDS samples has led to new insights into the pathophysiology of these disorders. Of particular interest is the recent ...

    Research Article last updated 01/09/2012 - 2:04pm.