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  1. High-dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

    ... granulocyte colony stimulating factor until neutrophil recovery, transfusion support, and antimicrobial prophylaxis. ...

    Research Article last updated 08/15/2016 - 11:49am.

  2. Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

    ... granulocyte therapy, and post-transfusion absolute neutrophil count, stratified by HLA alloimmunization status. ... with survival. The mean post-transfusion absolute neutrophil count did not differ significantly between response groups (i.e. ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Prediction of adverse events during Intensive Induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

    ... baseline grade 4 neutropenia (i.e. absolute neutrophil count <500 cells/µL) was associated with development of fever ... cycle, grade 4 neutropenia was associated with delayed neutrophil count recovery (P<0.0001). Low monocyte and lymphocyte ...

    Research Article last updated 01/07/2014 - 12:42pm.

  4. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... one, who died due to encephalopathy on day 20, achieved neutrophil engraftment a median of 18.5 days after HSCT with ... regimen with half-dose CY and FDR is effective for achieving neutrophil engraftment and complete donor-type chimerism. However, subsequent ...

    Research Article last updated 03/06/2014 - 11:00am.

  5. Association between donor leukocyte telomere length and survival after unrelated allogeneic hematopoietic cell transplantation for severe aplastic anemia

    ... MAIN OUTCOMES AND MEASURES: Overall survival, neutrophil recovery, and acute and chronic graft-vs-host disease, as ... There was no association between donor telomere length and neutrophil engraftment at 28 days (cumulative incidence, 86% vs 85%; ...

    Research Article last updated 03/03/2015 - 11:48am.

  6. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... from unrelated umbilical cord were infused on day 1. Neutrophil engraftment was achieved in all 17 patients in a median ...

    Research Article last updated 09/04/2014 - 11:22am.

  7. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    ... fibrosis (89%) and severe fibrosis (75%) (P=0.009). Neutrophil engraftment occurred later in patients with mild or moderate ...

    Research Article last updated 07/28/2014 - 8:21am.

  8. Epidemiology and risk factors for infections in myelodysplastic syndromes.

    ... = 2.7, 95% CI = 1.7-4.1, P < 0.0001), nadir absolute neutrophil count <500/mL (HR = 1.8, 95% CI = 1.2-2.7, P < 0.007), chronic ...

    Research Article last updated 09/17/2013 - 2:12pm.

  9. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... UD, and 10 mismatched UD). All patients showed neutrophil and platelet engraftment . Cumulative incidence ...

    Research Article last updated 05/14/2013 - 1:00pm.

  10. Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia

    ... 2009 and July 2012. Among the 12 patients, 11 achieved neutrophil engraftment at a median of 10 days (range, 9 to 13 days) ...

    Research Article last updated 03/05/2013 - 8:11am.