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  1. Loss of expression of neutrophil proteinase-3: a contributory factor in thrombotic risk in paroxysmal nocturnal hemoglobinuria.

    ... co-localizes with glycosylphosphatidyl inositol -linked neutrophil antigen B1, absent in patients with paroxysmal nocturnal ... and Methods: We compared expression of proteinase 3 and neutrophil antigen B1 by flow cytometry and western blotting in normal ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Predictors of early mortality after rabbit antithymocyte globulin as first-line treatment in severe aplastic anemia

    ... ratio [OR] 5.06, P = 0.001) and baseline absolute neutrophil count (ANC) ≤ 0.1 × 109/L (OR 7.64, P < 0.001) were ... rabbit ATG due to a higher age and very low pre-treatment neutrophil count. Bone Marrow ...

    Research Article last updated 09/13/2017 - 7:45am.

  3. Infectious complications in patients with myelodysplastic syndromes: a review of the literature with emphasis on patients treated with 5-azacitidine

    ... number of cytopenias and thereby indirectly taking the neutrophil count into consideration2 . Finally, in 2012 the revised IPSS ...

    Research Article last updated 04/14/2017 - 10:41am.

  4. De-escalation empirical antibiotic therapy improved survival for patients with severe aplastic anemia treated with antithymocyte globulin.

    ... therapy. On day 30, more patients had increased absolute neutrophil count in de-escalation group compared with non-de-escalation ...

    Research Article last updated 02/15/2017 - 1:45pm.

  5. Clinical applications of haploidentical hematopoietic stem cell transplantation in severe aplastic anemia

    ... 8 patients with the average time of 14.8d for absolute neutrophil count (ANC) > 0.5×109/L, and the average time of 15.0d for ...

    Research Article last updated 02/03/2017 - 9:36am.

  6. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... was 30 (range, 11 to 69) years. The median time to neutrophil recovery over 1000 × 103/mm3 for 3 consecutive days was 19 ...

    Research Article last updated 01/24/2017 - 10:04am.

  7. Horse ATG Saves Young Equestrian

    ... There was a scare in June of 2016 when her ANC (absolute neutrophil count) levels had dropped significantly. The doctors decided to ...

    Patient Chronicle last updated 01/04/2017 - 3:06pm.

  8. Comparable outcomes between younger (⩽40 years) and older (&gt;40 years) adult patients with severe aplastic anemia after HLA-matched sibling stem cell transplantation using fludarabine-based conditioning

    ... years) patients. No primary graft failure was observed. Neutrophil engraftment was significantly faster in the YAG compared ...

    Research Article last updated 11/28/2016 - 9:28am.

  9. High-dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

    ... granulocyte colony stimulating factor until neutrophil recovery, transfusion support, and antimicrobial prophylaxis. ...

    Research Article last updated 11/01/2016 - 1:49pm.

  10. Bone marrow transplantation versus immunosuppressive therapy in patients with acquired severe aplastic anemia

    ... sibling, or the first-line IST. Young patients with low neutrophil counts benefited of the first-line BMT; the opposite was true for older patients with higher neutrophil counts; and a third intermediate group of patients had comparable ...

    Research Article last updated 07/18/2016 - 10:11am.