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  1. Loss of expression of neutrophil proteinase-3: a contributory factor in thrombotic risk in paroxysmal nocturnal hemoglobinuria.

    ... co-localizes with glycosylphosphatidyl inositol -linked neutrophil antigen B1, absent in patients with paroxysmal nocturnal ... and Methods: We compared expression of proteinase 3 and neutrophil antigen B1 by flow cytometry and western blotting in normal ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

    ... granulocyte therapy, and post-transfusion absolute neutrophil count, stratified by HLA alloimmunization status. ... with survival. The mean post-transfusion absolute neutrophil count did not differ significantly between response groups (i.e. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Prediction of adverse events during Intensive Induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

    ... baseline grade 4 neutropenia (i.e. absolute neutrophil count <500 cells/µL) was associated with development of fever ... cycle, grade 4 neutropenia was associated with delayed neutrophil count recovery (P<0.0001). Low monocyte and lymphocyte ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... one, who died due to encephalopathy on day 20, achieved neutrophil engraftment a median of 18.5 days after HSCT with ... regimen with half-dose CY and FDR is effective for achieving neutrophil engraftment and complete donor-type chimerism. However, subsequent ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... from unrelated umbilical cord were infused on day 1. Neutrophil engraftment was achieved in all 17 patients in a median ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Epidemiology and risk factors for infections in myelodysplastic syndromes.

    ... = 2.7, 95% CI = 1.7-4.1, P < 0.0001), nadir absolute neutrophil count <500/mL (HR = 1.8, 95% CI = 1.2-2.7, P < 0.007), chronic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... UD, and 10 mismatched UD). All patients showed neutrophil and platelet engraftment . Cumulative incidence ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia

    ... 2009 and July 2012. Among the 12 patients, 11 achieved neutrophil engraftment at a median of 10 days (range, 9 to 13 days) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Cotransplantation of allogeneic mesenchymal and hematopoietic stem cells in children with aplastic anemia

    ... (range: 0.85-2.5 × 10(6)/kg). The mean time for neutrophil and platelet recovery was 12.3 and 13.8 days, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... were HLA DR15+ (hazard ratio = 0.46, P = .01). However, neutrophil recovery at day -28, platelet recovery at day -100, ...

    Research Article last updated 07/20/2018 - 5:14pm.