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  1. Infectious complications in patients with myelodysplastic syndromes: a review of the literature with emphasis on patients treated with 5-azacitidine

    ... of patients, about 30-50% of patients suffer from neutropenia of varying severity. Risk assessment was initially done based ... . Finally, in 2012 the revised IPSS included the severity of neutropenia into risk stratification3 . ...

    Research Article last updated 04/14/2017 - 10:41am.

  2. Prediction of adverse events during Intensive Induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

    ... (n=30). Among the entire cohort, baseline grade 4 neutropenia (i.e. absolute neutrophil count <500 cells/µL) was ... patients who received "7+3"-like induction, baseline grade 4 neutropenia remained associated with documented infection (P<0.0001) and ...

    Research Article last updated 01/07/2014 - 12:42pm.

  3. New treatment approved for certain high-risk AML

    ... fever with low white blood cell count (febrile neutropenia ), rash, swelling of the tissues (edema), nausea, inflammation ...

    Article last updated 08/30/2017 - 7:18am.

  4. Identifying bone marrow failure in children

    ... A baby might not have the energy to feed. Children with neutropenia might present with infections, ranging from mouth sores or skin ... had leukemia at age 7, that's a red flag. Neutropenia is common and not a reason for referral in and of itself. But if a ...

    Article last updated 03/15/2017 - 10:08am.

  5. Promising news for older AML patients

    ... in 32% of those on the 800-mg dose. Grade 3/4 febrile neutropenia occurred in 48% and 30%, respectively, and neutropenia in 40% and 32%. A phase 3 study of venetoclax at the 400-mg ...

    Article last updated 07/19/2017 - 11:19am.

  6. Immunosuppressive therapy for transplant-ineligible aplastic anemia patients

    ... patients are at risk of infection and hemorrhage due to neutropenia and thrombocytopenia and suffer from symptoms of ...

    Research Article last updated 03/02/2015 - 1:04pm.

  7. Marrow protein may be key to SCT success

    ... undergoing chemotherapy who develop febrile neutropenia , associated with low levels of white blood cells, might benefit ...

    Article last updated 08/29/2017 - 11:18am.

  8. Lenalidomide for del(5q) and Non-del(5q) Myelodysplastic Syndromes

    ... independence is 2 years, mainly at the expense of neutropenia and thrombocytopenia in the first courses of therapy. ... of duration of response, and 50% incidence of grade 3 and 4 neutropenia and thrombocytopenia compared to del(5q) patients. Recent data ...

    Research Article last updated 11/05/2012 - 9:37am.

  9. Infections in myelodysplastic syndromes: a review

    ... are associated with a risk of severe infections. While neutropenia is likely the main predisposing factor, several other immune ... in myelodysplastic syndromes but can transiently worsen neutropenia, may increase the risk of infection and their severity in this ...

    Research Article last updated 07/31/2012 - 1:39pm.

  10. Infections in patients with aplastic anemia.

    ... difference in the infections that they incur. Prolonged neutropenia is one of the largest risk factors for the development of ... with the invasive mycoses and bacteria. Recovery from neutropenia is directly related to survival, and supportive care plays ...

    Research Article last updated 10/11/2011 - 5:58pm.