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  1. Infectious complications in patients with myelodysplastic syndromes: a review of the literature with emphasis on patients treated with 5-azacitidine

    ... of patients, about 30-50% of patients suffer from neutropenia of varying severity. Risk assessment was initially done based ... . Finally, in 2012 the revised IPSS included the severity of neutropenia into risk stratification3 . Bone Marrow ...

    Research Article last updated 04/14/2017 - 10:41am.

  2. New treatment approved for certain high-risk AML

    ... fever with low white blood cell count (febrile neutropenia ), rash, swelling of the tissues (edema), nausea, inflammation ...

    Article last updated 08/30/2017 - 7:18am.

  3. Prediction of adverse events during Intensive Induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

    ... (n=30). Among the entire cohort, baseline grade 4 neutropenia (i.e. absolute neutrophil count <500 cells/µL) was ... patients who received "7+3"-like induction, baseline grade 4 neutropenia remained associated with documented infection (P<0.0001) and ...

    Research Article last updated 01/07/2014 - 12:42pm.

  4. Promising news for older AML patients

    ... in 32% of those on the 800-mg dose. Grade 3/4 febrile neutropenia occurred in 48% and 30%, respectively, and neutropenia in 40% and 32%. A phase 3 study of venetoclax at the 400-mg ...

    Article last updated 07/19/2017 - 11:19am.

  5. Identifying bone marrow failure in children

    ... A baby might not have the energy to feed. Children with neutropenia might present with infections, ranging from mouth sores or skin ... had leukemia at age 7, that's a red flag. Neutropenia is common and not a reason for referral in and of itself. But if a ...

    Article last updated 03/15/2017 - 10:08am.

  6. Marrow protein may be key to SCT success

    ... undergoing chemotherapy who develop febrile neutropenia , associated with low levels of white blood cells, might benefit ...

    Article last updated 08/29/2017 - 11:18am.

  7. Efficacy, safety, and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes

    ... common grade 3-4 treatment-emergent adverse events were neutropenia (52%) and leukopenia (39%). Pharmacokinetic profiles were ...

    Research Article last updated 02/03/2017 - 10:05am.

  8. Treatment of low-risk myelodysplastic syndromes

    ... good efficacy, but raised some safety concern. Although neutropenia is targeted symptomatically with growth factor ...

    Research Article last updated 01/26/2017 - 10:42am.

  9. Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-Analysis

    ... and 0.001, respectively). The incidences of grades 3-4 neutropenia , thrombocytopenia , leukopenia, anemia , deep ...

    Research Article last updated 11/28/2016 - 9:36am.

  10. Immunosuppressive therapy for transplant-ineligible aplastic anemia patients

    ... patients are at risk of infection and hemorrhage due to neutropenia and thrombocytopenia and suffer from symptoms of ...

    Research Article last updated 03/02/2015 - 1:04pm.