Search | Page 9 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. MDS Rounds: An AAMDSIF Visiting Faculty Program

    ... relationship between clinical symptoms and genetic mutation profiles. •    During the past decade, extensive research ...

    Page last updated 11/18/2016 - 12:55pm.

  2. Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

    ... with high risk MDS or AML treated with AZA. A TP53 mutation was found in 23 patients (37.1%), associated with complex ... OS was negatively influenced by the presence of TP53 mutation (median OS 12.4 months versus 23.7 months, p<10-4), abnormal ...

    Research Article last updated 06/02/2014 - 11:17am.

  3. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

    ... older persons, detection of an MDS-associated somatic mutation in a cytopenic patient without other evidence of MDS may cause ...

    Research Article last updated 06/03/2015 - 1:38pm.

  4. Non-t(6;9) and Non-Inv(3) Balanced Chromosomal Rearrangements Are Associated With Poor Survival Outcomes in Myelodysplastic Syndromes

    ... which might be influenced by the presence of SRSF2 mutation . Bone Marrow Diseases:  ...

    Research Article last updated 06/03/2015 - 8:44am.

  5. Clinical effect of point mutations in myelodysplastic syndromes

    ... myelodysplastic syndromes. We then examined whether the mutation status for each gene was associated with clinical variables, ... A total of 51% of all patients had at least one point mutation, including 52% of the patients with normal cytogenetics . ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. The molecular pathogenesis of the myelodysplastic syndromes

    ... a pathway not previously known as a target for mutation , in the MDS pathogenesis. Several regulators of signal ...

    Research Article last updated 03/04/2015 - 1:52pm.

  7. Aplastic Anemia & MDS International Foundation: Bone marrow failure disease scientific symposium 2012

    ... from patients with critically short telomeres and/or mutation in telomerase genes. The possibility of modulating telomere ...

    Research Article last updated 01/23/2015 - 3:36pm.

  8. Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes

    ... mutations, and between severe granulocytic dysplasia and mutation of ASXL1, RUNX1, TP53 and SRSF2 genes. In myeloid neoplasms with ...

    Research Article last updated 07/07/2014 - 9:47am.

  9. Somatic mutations and epigenetic abnormalities in myelodysplastic syndromes

    ... prognosis, while some gene mutations (mainly TET2 mutation ), may be associated to better response to hypomethylating agents. ...

    Research Article last updated 03/06/2014 - 11:45am.

  10. Myelodysplastic syndromes with 5q deletion: pathophysiology and role of lenalidomide

    ... to lenalidomide. It is recommended to identify TP53 mutation early in the disease since it may change the decision regarding ...

    Research Article last updated 04/17/2014 - 11:29am.