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  1. Matthew J. Walter, MD

    ... MDS initiation is unknown. We will determine whether a mutation in one of these genes (U2AF1) affects blood cell formation in mice ... to MDS initiation is unknown. We are studying a mutation in one of these genes ( U2AF1 ) to determine how it alters ...

    Grant Recipient last updated 08/18/2014 - 10:07am.

  2. Resistance to Hypomethylating Agents in the Treatment of MDS

    ... which help with the prognosis for a patient with MDS. Mutation status of specific genes is another tool that is coming to the ... patients with MDS.  For example, MDS that harbors a p53 mutation has a worse prognosis than those without a p53 mutation. We are ...

    Interview last updated 06/17/2014 - 9:15am.

  3. Research Overview - Recent Past Progress and Projections for the Near-Term

    ... Or, the translational science may involve studying the mutation that turns on the activity of an enzyme in a critical regulatory ...

    Interview last updated 02/10/2014 - 9:40am.

  4. Research Overview – Recent Past Progress and Projections for the Near-Term

    ... relevance. Or, the translational part may involve the mutation of an enzyme that turns it on. With that, we want to know if we ...

    Page last updated 01/14/2014 - 11:47am.

  5. Interviews with the Experts MDS Genomics: Providing ‘Street View’ Directions of Disease

    ... and it takes time to explain normal function, let alone mutation , and we respect our doctors’ busy schedules. But patients need ...

    Interview last updated 09/23/2014 - 9:30am.