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  1. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... Must be <75 years old with no 7/8 or 8/8 HLA -matched sibling donor One or more potential related mismatched donors (e.g. biologic parent (s) or siblings (full or half) ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  2. 5K Run & Walk Houston, Texas

    ... had a bone marrow transplant thanks to an anonymous matched donor, but it failed to work. A second transplant the following year ... (MDS), paroxysmal nocturnal hemoglobinuria (PNH) and related bone marrow failure diseases. The Foundation’s strength ...

    Friendraising Walk last updated 03/24/2017 - 3:44pm.

  3. Overview of stem cell transplantation for aplastic anemia

    ... be the patient’s brother or sister.  This is called a “matched sibling or related donor”.  If a patient does not have a matched sibling or related ...

    Research Review last updated 05/02/2016 - 9:31am.

  4. Total Marrow Irradiation for Refractory Acute Leukemia

    ... UCB graft will be composed of two partially HLA matched units. Each unit must be matched at 4-6 HLA loci to the recipient and ... total graft dose must be >3 x 107 MNC/kg HLA- matched related donor (6/6 or 5/6 antigen match) HLA-matched unrelated adult ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  5. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... with intermediate or high risk IPSS score, or treatment related MDS. c. CML resistant to tyrosine kinase treatment in a first or ... donate peripheral blood: a. Related donor, 8/8 HLA -matched for HLA-A, -B, C and DR matched or, b. Matched Unrelated Donor ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.

  6. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... undergoing transplantation of bone marrow from half-matched (haploidentical) donors. This approach has extended the transplant option to patients who do not have matched related or unrelated donors, especially for patients from ethnic minority ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  7. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... condition regimen with UCBT, double cord UCBT, matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood ... Patients must have a 4/6, 5/6 or 6/6 HLA matched related or unrelated UCB unit available that will deliver a ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  8. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... palifermin improves the results of allogeneic SCT from HLA-matched unrelated donors. Objective: - To see if high doses of ... chemotherapy . Secondary AML, defined as AML related to antecedent myeloid neoplasm or cytotoxic chemotherapy. ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  9. CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

    ... Must have a human leukocyte antigen ( HLA )-matched or single allele-mismatched adult sibling serving as donor Must ... prior therapy are considered to be at high risk for regimen related toxicity associated with fully ablative transplant conditioning, and ...

    Clinical Trial last updated 04/29/2016 - 12:36pm.

  10. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... years at initial referral with no available and suitably matched related or unrelated donor . Acute myelogenous leukemia ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.