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  1. Strong results for SAA patients at Johns Hopkins

    ... called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common ... therapy or other drug treatments. None had access to a related fully matched bone marrow donor but did have an available and willing ...

    Article last updated 02/07/2017 - 11:05am.

  2. Recent developments in bone marrow transplants

    ... increased risk for graft-versus-host disease (GVHD)–related mortality in adults with T-cell leukemia/lymphoma. Patients with ... of a HSCT from an umbilical cord blood source or HLA–matched unrelated donor . Repeated infusions of mesenchymal stromal ...

    Article last updated 11/16/2016 - 2:56pm.

  3. Major news in BMT with half-match donors

    ... primary investigator of many UT Southwestern clinical trials related to bone marrow transplantation. Mr. Dandridge enrolled in one such ... peripheral blood stem cell transplant from a partially matched relative. Immune cells (T cells) from the relative (donor) are ...

    Article last updated 06/14/2016 - 3:02pm.

  4. Stem Cell Transplantation: What Happens Behind the Scenes?

    ... Match®) registry and from this, I can identify unrelated matched donors or cord blood units for the recipient. Here at NIH, I work with ... the HLA and typing laboratories, the apheresis center when related donors are involved, radiology, molecular hematology, and so much more. ...

    Interview last updated 01/18/2018 - 1:28pm.

  5. Finding a Stem Cell Donor

    ... away. Only about 3 out of every 10 people can find a matched related donor . And it can take a long time to find a matched unrelated ...

    Page last updated 05/14/2015 - 9:46am.

  6. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... count < 20 x10^9/L No suitable fully matched related (6/6 match for human leukocyte antigen ( HLA )-A and B at ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  7. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... we began aimed at helping patients that did not have an HLA matched donor started about 12 years ago. This is when we tried to come up with ... rates that are comparable with those from the fully matched, related donors. The idea now is that if we can get much higher number of ...

    Interview last updated 10/04/2017 - 1:36pm.

  8. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... or ethnic background. Prior transfusions from selected donor (as this could have cause recipient alloimmunization against the donor) Women of childbearing potential who currently are pregnant (HCG+) or ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  9. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... or MPD Patients aged < 50 yrs at high risk for regimen related toxicity using standard high dose regimens; factors considered high ... antigen ( HLA )-identical related or an HLA-matched unrelated donor (Fred Hutchinson Cancer Research Center [FHCRC] ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  10. Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation

    ... 5-AzaC and the effect on grade II-IV GvHD when given after matched unrelated donor transplant (MUD). ... informed consent prior to participation in the study and any related procedures being performed. The effects of azacitidine on the ...

    Clinical Trial last updated 05/02/2016 - 2:07pm.