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  1. Strong results for SAA patients at Johns Hopkins

    ... called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common ... therapy or other drug treatments. None had access to a related fully matched bone marrow donor but did have an available and willing ...

    Article last updated 02/07/2017 - 11:05am.

  2. Recent developments in bone marrow transplants

    ... increased risk for graft-versus-host disease (GVHD)–related mortality in adults with T-cell leukemia/lymphoma. Patients with ... of a HSCT from an umbilical cord blood source or HLA–matched unrelated donor . Repeated infusions of mesenchymal stromal ...

    Article last updated 11/16/2016 - 2:56pm.

  3. Major news in BMT with half-match donors

    ... primary investigator of many UT Southwestern clinical trials related to bone marrow transplantation. Mr. Dandridge enrolled in one such ... peripheral blood stem cell transplant from a partially matched relative. Immune cells (T cells) from the relative (donor) are ...

    Article last updated 06/14/2016 - 3:02pm.

  4. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... or ethnic background. Prior transfusions from selected donor (as this could have cause recipient alloimmunization against the donor) Women of childbearing potential who currently are pregnant (HCG+) or ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  5. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... source identified for allogeneic transplantation, either related (7/8 or 8/8 allele matched or haploidentical), unrelated (7/8 or 8/8 allele match) donor, or cord ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  6. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... should be no readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one ...

    Clinical Trial last updated 06/06/2016 - 3:37pm.

  7. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... should be no readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one ...

    Clinical Trial last updated 06/03/2016 - 2:54pm.

  8. Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease

    ... assess complication rates for genetically ( HLA ) matched related donor combined ...

    Clinical Trial last updated 06/06/2016 - 3:04pm.

  9. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... Must be <75 years old with no 7/8 or 8/8 HLA -matched sibling donor One or more potential related mismatched donors (e.g. biologic parent (s) or siblings (full or half) ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  10. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... or MPD Patients aged < 50 yrs at high risk for regimen related toxicity using standard high dose regimens; factors considered high ... antigen ( HLA )-identical related or an HLA-matched unrelated donor (Fred Hutchinson Cancer Research Center [FHCRC] ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.