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  1. Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation.

    ... patients received alemtuzumab and 55 ATG-based regimens. A matched sibling donor (MSD) was used in 87 (56%), matched unrelated donor (MUD) in 60 (39%) and other related or mismatched unrelated donor (UD) in 8 (5%) patients. Engraftment ...

    Research Article last updated 08/15/2013 - 9:45am.

  2. Recent developments in bone marrow transplants

    ... increased risk for graft-versus-host disease (GVHD)–related mortality in adults with T-cell leukemia/lymphoma. Patients with ... of a HSCT from an umbilical cord blood source or HLA–matched unrelated donor . Repeated infusions of mesenchymal stromal ...

    Article last updated 11/16/2016 - 2:56pm.

  3. Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

    ... (HCT) from human leukocyte antigen ( HLA ) matched related donor (MRD) and matched unrelated donors (MUD) produces similar ...

    Research Article last updated 08/06/2013 - 2:12pm.

  4. Unrelated cord blood transplantation in a child with very severe aplastic anemia

    ... in the absence of a human leukocyte antigen - matched related donor (MRD). For SAA patients with complications such as bacterial ...

    Research Article last updated 02/04/2013 - 1:41pm.

  5. Allogeneic transplantation for aplastic anemia

    ... Search terms included severe aplastic anemia, HLA -matched sibling, unrelated donor , hematopoietic stem cell ... older patients ranging from 50-70%. The risks of transplant-related morbidity and mortality increase with age and explain the observed ...

    Research Article last updated 07/03/2012 - 2:57pm.

  6. Major news in BMT with half-match donors

    ... primary investigator of many UT Southwestern clinical trials related to bone marrow transplantation. Mr. Dandridge enrolled in one such ... peripheral blood stem cell transplant from a partially matched relative. Immune cells (T cells) from the relative (donor) are ...

    Article last updated 06/14/2016 - 3:02pm.

  7. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    ... had failed initial CSA treatment and lacked a HLA -matched sibling donor, underwent co-transplantation of unrelated donor ... primary graft failure, the reason for which may be related to a long history (>17 years) of SAA. The other four patients achieved ...

    Research Article last updated 11/26/2013 - 11:14am.

  8. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... by the age of MDS patients, high rates of transplant-related mortality (TRM) and availability of a suitable HLA -matched donor. Results from several large centres indicated 3-year overall ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Haploidentical transplantation in patients with acquired aplastic anemia

    ... antithymocyte globulin and lacking an HLA -matched related or unrelated donor . The platforms of both ex vivo T-cell-depleted and unmanipulated ...

    Research Article last updated 02/04/2013 - 2:16pm.

  10. Finding a Stem Cell Donor

    ... away. Only about 3 out of every 10 people can find a matched related donor . And it can take a long time to find a matched unrelated ...

    Page last updated 05/14/2015 - 9:46am.