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  1. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... patients had haploidentical donors (HIDs), and 69 had matched related donors (MRDs) for HSCT. The median times for myeloid engraftment ...

    Research Article last updated 02/03/2017 - 9:40am.

  2. Foundation Update - October 2017

    ... epitome of resilience as she has waited for years to find a matched donor. She has devoted this time to helping other patients by enlarging ... been added on personalized medicine and the fundamentals of related diseases, such as AML, CMML, GVHD, MPNs and PRCA. The remaining 2017 ...

    Article last updated 11/30/2017 - 2:30pm.

  3. Repurposing older drugs to help prevent GVHD

    ... disease (GVHD) after reduced-intensity conditioning, related donor hematopoietic cell transplantation (HCT). However, its safety and ... receive myeloablative HCT from an available 8/8- HLA matched URD. Patients received GVHD prophylaxis with tacrolimus and ...

    Article last updated 10/18/2017 - 8:48am.

  4. Professionals

    Resources Health care providers are the primary source of information for their patients, but they too need access to factual and...

    Page last updated 05/03/2018 - 2:28pm.

  5. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... hematopoietic stem cell transplantation (AlloHSCT) from matched related donors (MRD) has resulted in the highest survival rates in children ...

    Research Article last updated 04/09/2014 - 9:11am.

  6. First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.

    ... cells is a first-line treatment option if HLA -matched related donors are available. First-line immunosuppressive therapy may ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Alternative donors for allogeneic hematopoietic stem cell transplantation in poor-risk AML in CR1

    ... with poor-risk AML in CR1 receiving an alloHSCT using matched related donor (MRD, n = 3511) or alternative donors, including 10/10 (n = ...

    Research Article last updated 03/09/2017 - 8:22am.

  8. Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation.

    ... patients received alemtuzumab and 55 ATG-based regimens. A matched sibling donor (MSD) was used in 87 (56%), matched unrelated donor (MUD) in 60 (39%) and other related or mismatched unrelated donor (UD) in 8 (5%) patients. Engraftment ...

    Research Article last updated 08/15/2013 - 9:45am.

  9. Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

    ... (HCT) from human leukocyte antigen ( HLA ) matched related donor (MRD) and matched unrelated donors (MUD) produces similar ...

    Research Article last updated 08/06/2013 - 2:12pm.

  10. Drug reduces acute GVHD in unrelated HSCTs

    ... graft-versus-host disease (GVHD) in the setting of matched unrelated donor myeloablative conditioning hematopoietic ... and resulted in a low incidence of acute GVHD following related donor-reduced intensity conditioning HSCT.2 In the phase II trial, ...

    Article last updated 02/27/2017 - 1:45pm.