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  1. Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies

    ... to produce an anti-cancer effect called large granular lymphocyte cellular expansion. Large granular lymphocytes are blood cells ... Researchers think that dasatinib may cause large granular lymphocyte expansion to happen in patients who have received a blood stem ...

    Clinical Trial last updated 05/03/2016 - 10:43am.

  2. Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

    ... Giving an infusion of the donor's T cells (donor lymphocyte infusion) after the transplant may help increase this effect. ... Therapeutic allogeneic lymphocytes Undergo donor lymphocyte infusion Other Names: Allogeneic Lymphocytes ALLOLYMPH Drug: ...

    Clinical Trial last updated 05/03/2016 - 10:51am.

  3. Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... Giving an infusion of the donor's T cells (donor lymphocyte infusion) after the transplant may help increase this effect. ...

    Clinical Trial last updated 05/03/2016 - 11:17am.

  4. Adoptive Transfer of Haplo-identical DLI for AML and MDS

    ... is that chemotherapy followed by donor lymphocyte infusion (DLI) from HLA -haploidentical donors is a safe ...

    Clinical Trial last updated 05/03/2016 - 9:59am.

  5. Jaroslaw Maciejewski, MD, PhD

    ... syndromes - aplastic anemia , MDS, large granular lymphocyte leukemia, PNH and myeloid malignancies. His research includes ...

    Leadership Award last updated 05/02/2016 - 2:27pm.

  6. Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer

    ... Giving an infusion of the donor's T cells (donor lymphocyte infusion) may help the patient's immune system see any remaining ...

    Clinical Trial last updated 04/29/2016 - 12:48pm.

  7. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... -3 and -2. TRANSPLANTATION: Patients undergo donor lymphocyte infusion (DLI) on day -6 and cluster of differentiation (CD)-34+ ... regimen Other Name: radiotherapy Biological: Donor Lymphocyte Infusion (DLI) Undergo DLI Other Name: buffy coat fusion ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  8. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... undergo total body irradiation (TBI) followed by a donor lymphocyte infusion (DLI) on day -6. TRANSPLANT: Patients undergo ... Undergo TBI Biological: T Cell-Depleted Donor Lymphocyte Infusion Undergo DLI Drug: Cyclophosphamide Given ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  9. Chronic Lymphocytic Leukemia (CLL)

    ... CLL do not have any symptoms when diagnosed. The high lymphocyte count is often found during routine blood tests. Some symptoms ...

    Topic section last updated 07/07/2016 - 3:18pm.

  10. Amer Zeidan, M.D.

    ... is by activating a protein called the Cytotoxic T-Cell Lymphocyte Antigen-4 (CTLA-4) which is present on the surface of T-cells ...

    Bio last updated 03/11/2016 - 1:41pm.