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  1. Comparison of Rabbit Antithymocyte Globulin (R-ATG) and Jurkat Cell-Reactive Anti-T Lymphocyte Globulin (ATG-F) as a First-line Treatment for Children with Aplastic Anemia

    ... globulin (R-ATG) and Jurkat cell-reactive anti- T lymphocyte globulin (ATG-F) in the treatment of childhood aplastic ... infection control. Absolute counts of peripheral blood lymphocyte (ALC) in various time points were dynamically measured after ATG ...

    Research Article last updated 04/09/2014 - 9:23am.

  2. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... By multivariate analysis, baseline platelet and lymphocyte count predicted for IST response at 3 and 6 months, ...

    Research Article last updated 09/13/2017 - 7:40am.

  3. Host immunity affects survival in myelodysplastic syndromes: Independent prognostic value of the absolute lymphocyte count.

    ... prognostic significance of the peripheral blood absolute lymphocyte count (ALC) has been carefully examined in lymphoid ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes

    ... more effective. Adjusting the timing and dose of donor lymphocyte infusion reduces the risk of graft-versus-host disease without jeopardizing the graft-versus-leukaemia effect of donor lymphocyte infusion. SUMMARY: Allogeneic haematopoietic stem cell ...

    Research Article last updated 09/24/2014 - 10:46am.

  5. Prognostic relevance of lymphocytopenia, monocytopenia and lymphocyte-to-monocyte ratio in primary myelodysplastic syndromes: a single center experience in 889 patients

    ... relevance of monocytopenia, lymphocytopenia and lymphocyte -to- monocyte ratio (LMR) in a cohort of 889 patients with ... were documented. In univariate analysis, subnormal absolute lymphocyte count (ALC) <0.9 × 109/l; P=0.001), ALC<1.2 × 109/l (P=0.0002), ...

    Research Article last updated 05/02/2017 - 10:37am.

  6. SGI-110 With Donor Lymphocyte Infusion (DLI) for Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) Relapsing Post Allogeneic Stem Cell Transplantation (AlloSCT)

    ... clinical research study is to learn if giving donor lymphocyte cells and SGI-110 will help control AML and MDS. The safety of ... mg/m2 subcutaneously daily, Days 1 to 5. Procedure: Donor Lymphocyte Infusion On Day 6 of Cycles 2, 4, and 6, participants receive a ...

    Clinical Trial last updated 04/29/2016 - 12:20pm.

  7. STAT3-mutations indicate the presence of subclinical T cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

    ... Large granular lymphocyte leukemia (LGL) is often associated with immune cytopenias and ...

    Research Article last updated 07/29/2014 - 11:59am.

  8. Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation

    ... with azacitidine combined with donor lymphocyte infusion (DLI) is a safe and effective approach for the ...

    Clinical Trial last updated 04/28/2016 - 10:42am.

  9. Clinical applications of haploidentical hematopoietic stem cell transplantation in severe aplastic anemia

    ... , fludarabine , pig anti-human lymphocyte immune globulin (p-ALG) and/or total body irradiation (TBI). The ...

    Research Article last updated 02/03/2017 - 9:36am.

  10. Aplastic Anemia: Alternative Immunosuppressive Treatments and Eltrombopag. A report from the 2014 EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties

    ... resulted in any benefit. Furthermore, the use of anti- lymphocyte agents other than h-ATG (rabbit-ATG, cyclophosphamide , ... standard h-ATG + CsA, irrespective of a more pronounced lymphocyte depletion observed with these alternative compounds. Thus, at least ...

    Research Article last updated 03/02/2015 - 11:53am.