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  1. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... donors has excellent results thus far. Our long term leukocyte engraftment rate is 85-90% with the same disease-free ... we hypothesize will reduce both the T cells that mediate leukocyte rejection and the B/ plasma cells that produce anti-donor ...

    Clinical Trial last updated 04/28/2016 - 9:09am.

  2. Clinical Trials Report for April 2016

    ... cyclophosphamide (cytoxan) for patients with human leukocyte antigen ( HLA ) matched unrelated (MUD) and mismatched ...

    Page last updated 08/10/2016 - 11:00am.

  3. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... and acute lymphoblastic leukemia (ALL); however, human leukocyte antigen ( HLA )-matched donor availability continues to be ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  4. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... Related donor must be an 8/8 match for human leukocyte antigen ( HLA )-A, -B, and -C at intermediate (or higher) ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.

  5. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... likely when the recipient and donor have similar human leukocyte antigens ( HLA ). Researchers want to see if the drug ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  6. Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies

    ... stem cell transplantation (HSCT) from Human Leukocyte Antigen ( HLA )-mismatched related donors for children and ...

    Clinical Trial last updated 04/29/2016 - 10:59am.

  7. Cord Blood Transplant

    ... Bone marrow or peripheral blood from a Human Leukocyte Antigen ( HLA ) matched sibling donor is the most commonly ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  8. Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis

    ... cyclophosphamide (cytoxan) for patients with human leukocyte antigen ( HLA ) matched unrelated (MUD) and mismatched ...

    Clinical Trial last updated 04/27/2016 - 9:38am.

  9. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... and hematopoietic cell transplantation (HCT) from human leukocyte antigen ( HLA )-haploidentical related donors for patients ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  10. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... bone marrow stem cell transplantation using an human leukocyte antigen ( HLA ) matched sibling donor, only about 25% of ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.