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  1. Treatment of myelodysplastic syndromes in elderly patients.

    ... age or comorbidities at diagnosis or lack of a human leukocyte antigen-identical donor. MDS in the elderly should be managed ...

    Research Article last updated 02/10/2012 - 9:43am.

  2. Allogeneic stem cell transplantation for myelodysplastic syndromes: critical for cure?

    ... unrelated donor . For patients who lack an human leukocyte antigen -compatible donor, autologous SCT, or chemotherapy ...

    Research Article last updated 11/16/2011 - 2:15pm.

  3. Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.

    ... 6p arms (6pLOH). The 6pLOH commonly involved the human leukocyte antigen ( HLA ) locus, leading to loss of one HLA ...

    Research Article last updated 10/12/2011 - 3:13pm.

  4. Alternative donor transplantation for aplastic anemia.

    ... severe aplastic anemia who do not have a human leukocyte antigen ( HLA )-identical sibling generally receive ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.

    ... of Health from 2000 to 2008. The pretreatment leukocyte age-adjusted telomere length of patients with severe aplastic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Effect of stem cell source on outcomes after unrelated donor transplantation in severe aplastic anemia

    ... or PBPC (n = 71) from unrelated donors matched at human leukocyte antigen -A, -B, -C, -DRB1. Hematopoietic recovery was similar ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Telomere length in myelodysplastic syndromes

    ... (MDS) remains unclear. We compared peripheral blood leukocyte (PBL) TL among cases of histologically confirmed MDS (n = 65) ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Telomere Length and Allogeneic Hematopoietic Cell Transplantation for Severe Aplastic Anemia

    ... Association (JAMA) evaluating the association between leukocyte telomere length and outcomes in 330 matched unrelated HSCT for ... centers around the world. They showed that longer donor leukocyte telomere length was associated with increased survival in patients ...

    Research Review last updated 05/02/2016 - 9:13am.

  9. Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC (ExpMACs)

    ... access for patients who lack a fully HLA ( Human leukocyte antigen ) matched sibling donor and who are candidates for ...

    Clinical Trial last updated 06/13/2016 - 1:47pm.

  10. Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    ... donors has excellent results thus far. Our long term leukocyte engraftment rate is 85-90% with the same disease-free ... we hypothesize will reduce both the T cells that mediate leukocyte rejection and the B/ plasma cells that produce anti-donor ...

    Clinical Trial last updated 04/28/2016 - 9:09am.