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  1. Prospective assessment of effects on iron-overload parameters of deferasirox therapy in patients with myelodysplastic syndromes.

    ... evaluating the effects of deferasirox on liver iron concentration (LIC), labile plasma iron (LPI) and pharmacokinetics (PK) along with serum ferritin values ... syndromes (MDS) and evidence of iron overload . Twenty-four heavily transfused MDS patients were enrolled in a ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. How we treat lower risk myelodysplastic syndromes.

    ... correction of anemia , alloimmunization, and organ iron overload (for which the role of iron chelation remains debated). Treatment ...

    Research Article last updated 05/14/2013 - 2:56pm.

  3. Supportive care in severe and very severe aplastic anemia

    ... bacterial and viral infections, transfusion strategy and iron chelation and assess the evidence basis. In fact, many recommendations for ... events like alloimmunization to blood products and iron overload have a significant impact on the prognosis of AA patients and need ...

    Research Article last updated 01/02/2013 - 2:32pm.

  4. Infections in myelodysplastic syndromes: a review

    ... T-, and NK-cell defects and the possible consequences of iron overload due to red blood cell transfusions. The advanced age of ...

    Research Article last updated 07/31/2012 - 1:39pm.

  5. The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes

    ... and quality of life (QoL), and are associated with iron overload , potentially leading to organ damage. QoL studies demonstrate that ...

    Research Article last updated 06/15/2012 - 2:03pm.

  6. Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: safety, efficacy, and unexpected laboratory phenomena

    ... of hemolysis , transfusion requirements, and serum iron parameters were analyzed. Lactate dehydrogenase levels were ... iron depletion therapy should be considered in the case of overload. Bone Marrow Diseases:  ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Iron Overload and MDS

    PubMed Abstract:  Iron overload and chelation therapy in myelodysplastic syndromes ...

    Research Review last updated 05/02/2016 - 9:18am.

  8. Understanding and Managing Iron Overload in MDS

    ... Webinar Iron plays an important role in keeping your body healthy. Having enough iron ... can be harmful. Having too much iron is known as iron overload . This can happen when you get lots of blood transfusions. ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  9. Iron Overload in Acquired Anemias

    ... Leitch presents information on transfusion dependence, iron overload (IOL) and survival in MDS. IOL, ICT & organ function will also be ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  10. Fund Your Research

    ... (e.g., blood clotting/ thrombosis in PNH, iron overload in MDS, etc.); and, Research regarding inherited bone marrow ...

    Page last updated 11/29/2016 - 2:11pm.