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  1. Comparison of 24-month outcomes in chelated and non-chelated lower-risk patients with myelodysplastic syndromes in a prospective registry

    ... 600 lower-risk MDS patients (pts) with transfusional iron overload . Clinical outcomes were compared between chelated and nonchelated ...

    Research Article last updated 01/08/2014 - 9:35am.

  2. Iron status and treatment modalities in transfusion-dependent patients with myelodysplastic syndromes.

    ... Transfusion dependency and iron overload are common among patients with myelodysplastic syndromes ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Iron chelation therapy in myelodysplastic syndromes.

    ... transfusion dependency can be long lasting, leading to iron overload . Iron chelation therapy may be a therapeutic option for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

    ... of packed red blood cells leading to a secondary iron overload which might result in organ damage. Therefore, sufficient iron ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Increased parameters of oxidative stress and its relation to transfusion iron overload in patients with myelodysplastic syndromes.

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    Research Article last updated 06/28/2013 - 1:33pm.

  6. The role of iron chelation therapy for patients with myelodysplastic syndromes.

    ... The appropriate role of iron chelation therapy in the management of patients with ... with evidence suggesting transfusion-associated iron overload , is an important component of high-quality MDS patient care. Other ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Iron overload in myelodysplastic syndromes. Introduction.

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    Research Article last updated 10/11/2011 - 5:58pm.

  8. Iron overload in myelodysplastic syndromes.

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    Research Article last updated 10/11/2011 - 5:58pm.

  9. Efficacy and safety of deferasirox in myelodysplastic syndromes

    ... damage due to accumulation of non- transferrin -bound iron with consequent increased oxidative stress. Iron chelation has been ... plasma iron, independently from the efficacy on iron overload . Deferasirox is a potent NF-kB inhibitor, tested in vivo and on ...

    Research Article last updated 03/05/2013 - 9:15am.

  10. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

    ... the presence of abnormal sideroblasts characterized by iron overload in the mitochondria, called RS. Based on the high frequency of ...

    Research Article last updated 07/31/2012 - 12:50pm.