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  1. Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome

    ... The risk and clinical significance of cardiac iron overload due to chronic transfusion varies with the underlying disease. ...

    Research Article last updated 03/22/2017 - 10:46am.

  2. Myelodysplastic Syndromes and Iron Chelation Therapy

    ... of chelation therapies to the benefit of patients with iron overload . However, extrapolation of learnings from thalassemia to the ...

    Research Article last updated 03/22/2017 - 9:11am.

  3. Decision points in the treatment of transfusional iron overload in patients with myelodysplastic syndromes: why, when, and how to chelate

    ... frequent use of red blood cell transfusions lead to iron accumulation and ultimately organ damage. Whether iron-reducing interventions such as chelation therapy can improve outcomes in ... articles from PubMed on the topic of iron overload (IO) in MDS, and the use of iron chelation therapies (ICTs) to ...

    Research Article last updated 01/26/2017 - 10:17am.

  4. Experts expound on iron overload in MDS

    ... Article Link:  Excess Iron in MDS Article Source:  ... are inevitable. And so, these include not only iron overload in the organs such as the liver and the heart, which can lead to ...

    Article last updated 10/19/2016 - 10:04am.

  5. Relation between chelation and clinical outcomes in lower-risk patients with myelodysplastic syndromes: Registry analysis at 5 years

    ... Prospective data are needed to ascertain the impact of iron chelation therapy in patients with myelodysplastic syndromes . ... myelodysplastic syndromes and transfusional iron overload . In an interim analysis at 24 months, we previously reported that ...

    Research Article last updated 03/22/2017 - 11:24am.

  6. Management of lower-risk myelodysplastic syndromes without del5q: Current approach and future trends

    ... combination treatment modalities, and management of iron overload . Lastly, we overview the most promising investigational agents for ...

    Research Article last updated 03/22/2017 - 9:46am.

  7. Management of iron overload in myelodysplastic syndromes: combined deferasirox and deferoxamine in a patient with liver disease

    Journal Title:  Blood Transfus Primary Author:  Cerchione C Author(s):  Cerch...

    Research Article last updated 12/09/2016 - 2:46pm.

  8. MDS Follows Two Misdiagnoses

    ... now, staying more stable, but I'm now fighting high iron overload because of transfusions.  I’m using deferoxamine (Desferal®) ...

    Patient Chronicle last updated 12/27/2016 - 7:23am.

  9. When is iron overload deleterious, and when and how should iron chelation therapy be administered in myelodysplastic syndromes?

    ... Iron overload in MDS starts even before patients become red-blood cell ...

    Research Article last updated 03/06/2014 - 11:39am.

  10. Can iron overload in patients with lower-risk myelodysplastic syndromes be reduced using erythropoiesis-stimulating agents?

    ... Iron overload (IOL) portends inferior outcome in myelodysplastic syndromes ...

    Research Article last updated 12/09/2015 - 8:52am.