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  1. The role of iron chelation therapy for patients with myelodysplastic syndromes.

    ... The appropriate role of iron chelation therapy in the management of patients with myelodysplastic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Iron chelation therapy in myelodysplastic syndromes.

    ... To understand how to appropriately recognize and manage iron overload with iron chelation therapy (ICT) in patients with myelodysplastic syndromes ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

    ... of packed red blood cells leading to a secondary iron overload which might result in organ damage. Therefore, sufficient iron chelation therapy in selected patients is mandatory. Deferasirox ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Adequate iron chelation therapy for at least six months improves survival in transfusion-dependent patients with lower risk myelodysplastic syndromes

    ... syndromes (MDS) require transfusions at the risk of iron overload and associated organ damage, and death. Emerging evidence indicates that iron chelation therapy (ICT) could reduce mortality and improve survival in ...

    Research Article last updated 07/29/2014 - 12:11pm.

  5. Optimizing therapy for iron overload in the myelodysplastic syndromes: recent developments.

    ... cells for anaemia, placing them at risk of transfusional iron overload . In β-thalassaemia major, transfusional iron overload leads to organ dysfunction and death; however, with iron chelation therapy , organ function is improved, and survival improved to ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Iron Chelation

    ... Red blood cells contain iron. Each time you get a red blood cell transfusion you are putting ... iron overload? Iron chelation therapy is used when you have a condition called iron ...

    Topic section last updated 06/23/2016 - 3:56pm.

  7. Can iron overload in patients with lower-risk myelodysplastic syndromes be reduced using erythropoiesis-stimulating agents?

    ... Iron overload (IOL) portends inferior outcome in myelodysplastic ... had ferritin levels available, and were not receiving iron chelation therapy. Baseline characteristics were not significantly different ...

    Research Article last updated 12/09/2015 - 8:52am.

  8. Iron status and treatment modalities in transfusion-dependent patients with myelodysplastic syndromes.

    ... Transfusion dependency and iron overload are common among patients with myelodysplastic syndromes ... progression and shorter survival. Guidelines recommend iron chelation therapy to manage iron overload, however little is known about the ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Myelodysplastic syndromes and the role of iron overload.

    ... of myelodysplastic syndromes (MDS) and iron overload , recent clinical findings that highlight the importance of ... and recommendations for initiating and maintaining iron chelation therapy (ICT) are summarized. SUMMARY: MDS are a ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Impact of iron overload in myelodysplastic syndromes.

    ... red blood cell transfusions, which can lead to iron overload . Some patients may already have iron overload before ... MDS, especially those with lower-risk disease. Iron chelation therapy may be beneficial in these patients. ...

    Research Article last updated 10/11/2011 - 5:58pm.