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  1. Relation between chelation and clinical outcomes in lower-risk patients with myelodysplastic syndromes: Registry analysis at 5 years

    ... Prospective data are needed to ascertain the impact of iron chelation therapy in patients with myelodysplastic syndromes . The ...

    Research Article last updated 03/22/2017 - 11:24am.

  2. Myelodysplastic Syndromes and Iron Chelation Therapy

    ... technologies and of an expanded knowledge and application of chelation therapies to the benefit of patients with iron overload . However, extrapolation of learnings from thalassemia to the ...

    Research Article last updated 03/22/2017 - 9:11am.

  3. Decision points in the treatment of transfusional iron overload in patients with myelodysplastic syndromes: why, when, and how to chelate

    ... frequent use of red blood cell transfusions lead to iron accumulation and ultimately organ damage. Whether iron-reducing interventions such as chelation therapy can improve outcomes in this population is currently under ...

    Research Article last updated 01/26/2017 - 10:17am.

  4. Experts expound on iron overload in MDS

    ... Article Link:  Excess Iron in MDS Article Source:  ... anemias know a lot about iron overload and managing iron chelation therapy . But for hematologists like myself that trained mostly in ...

    Article last updated 10/19/2016 - 10:04am.

  5. Iron overload and chelation therapy in myelodysplastic syndromes

    ... Iron overload remains a concern in MDS patients especially those requiring ... unmask silent ones. Under these circumstances, iron chelation therapy could play an integral role in the management of these ...

    Research Article last updated 03/12/2014 - 10:20am.

  6. Aplastic anemia

    ... include transfusion, G-CSF, and the administration of iron chelation agents, as well as dealing specifically with individual symptoms. ...

    Research Article last updated 11/01/2016 - 1:58pm.

  7. Toward resolving the unsettled role of iron chelation therapy in myelodysplastic syndromes

    ... syndromes (MDS) patients, eventually develop iron overload . Iron toxicity, via oxidative stress, can damage cellular ... organ function. In thalassemia major patients, iron chelation therapy lowered iron levels with recovery of cardiac and liver ...

    Research Article last updated 04/16/2014 - 12:34pm.

  8. When is iron overload deleterious, and when and how should iron chelation therapy be administered in myelodysplastic syndromes?

    ... Iron overload in MDS starts even before patients become red-blood cell ... which increase the level of oxidative stress. Iron chelation therapy (ICT) can rapidly lower NTBI and LPI and more slowly ...

    Research Article last updated 03/06/2014 - 11:39am.

  9. Iron chelation therapy in myelodysplastic syndromes: where do we stand?

    ... Anemia leading to transfusion dependency (TD) and iron overload (IO) is commonly observed in patients with ... documentation of the beneficial effects of iron chelation therapy (ICT) on organ function and survival in MDS patients with ...

    Research Article last updated 09/09/2013 - 10:56am.

  10. Iron chelation therapy in myelodysplastic syndromes.

    ... transfusion dependency can be long lasting, leading to iron overload . Iron chelation therapy may be a therapeutic option for these patients, ...

    Research Article last updated 10/11/2011 - 5:58pm.