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  1. Total Marrow Irradiation for Refractory Acute Leukemia

    ... Drug: cyclophosphamide 60 mg/kg/day intravenous x 2 days pre-transplant, total dose 120 mg/kg Other Name: ... Drug: Fludarabine 25 mg/m2/day intravenous as a 1 hour infusion for consecutive 3 days pre-transplant, total dose 75 mg/m2 Other ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  2. An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)

    ... Drug: Azacitidine Azacitidine intravenous or subcutaneous formulation. Drug: Pevonedistat Pevonedistat intravenous infusion. ...

    Clinical Trial last updated 04/28/2016 - 1:58pm.

  3. Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases

    ... IV beginning on day +1 after umbilical cord blood (UCB) infusion. G-CSF will be administered daily until the absolute neutrophil count ... and -6 after fludarabine. Cyclophosphamide 60mg/kg/day intravenous (IV) x 2 days, total dose 120 mg/kg (days -7 and -6) Dosing is ...

    Clinical Trial last updated 04/28/2016 - 12:05pm.

  4. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... chemotherapy and/or radiation therapy, followed by an infusion of their donor's bone marrow or blood stem cells . The ... Drug: Cytarabine Given by either intrathecal (IT) or intravenous (IV) route. Other Names: Cytosine arabinoside Ara-C ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  5. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... least 4 hours before the peripheral blood stem cell (PBSC) infusion (MT2001-10). Study Arm (s) Experimental: Cohort 1 ... on day -3 at a dose of 3 gram/day divided in 2 or 3 doses. Intravenous (IV) route between days -3 and +5, then may change to PO between ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  6. Growth Factors

    ... (shot) under the skin. They may also be given as an infusion into a vein through an intravenous IV. You may also be trained to give these to yourself at home. ...

    Topic section last updated 04/06/2016 - 12:37pm.

  7. A Study of CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

    ... (Part B), clinical study of CC-90002, administered by intravenous (IV) infusion, in subjects with relapsed and/or primary refractory AML and ...

    Clinical Trial last updated 04/27/2016 - 1:31pm.

  8. Busulfan and Cyclophosphamide Followed By ALLO BMT

    ... through -4 (prior to transplant): given intravenously (IV) infusion over 2 hours every 6 hours following dose, administration and ... Days -3 and -2 (prior to transplantation): given as a 2 hour intravenous infusion with a high volume fluid flush and mesna per institutional ...

    Clinical Trial last updated 04/29/2016 - 1:23pm.

  9. TBI Dose De-escalation for Fanconi Anemia

    ... receive the same treatment. The stem cells are given as an infusion into the subject's existing catheter over 1-2 hours on day 0.5. On the ... via central line (i.e. Hickman or Broviac),35 mg/m^2 intravenous (IV) Other Name: fludara Procedure: Total Body ...

    Clinical Trial last updated 04/28/2016 - 9:06am.

  10. PNH - Treatment (OLD)

    ... as an injection (shot) in the arm, abdomen or thigh or by infusion into a vein (intravenous IV). Your doctor may ask you to take a white blood cell ...

    Topic section last updated 03/10/2016 - 11:09pm.