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  1. New therapeutics for myelodysplastic syndromes

    ... Dr. List outlines the rationale for MDS-directed drug development efforts and describes several emerging agents currently or ... Historically, this approach has consisted primarily of immunosuppressive therapy and been restricted in effectiveness to early stage ...

    Research Review last updated 05/02/2016 - 9:28am.

  2. Growth Factors

    ... in the bone marrow to stimulate. They may be used after immunosuppressive therapy is done and bone marrow stem cells start to come ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 04/06/2016 - 12:37pm.

  3. Reduced Intensity Double Umbilical Cord Blood Transplantation

    ... radiation on day 0 (same day as transplant) Immunosuppressive Therapy Tacrolimus and sirolimus beginning day -3, ... Associated Drug(s):  Fludarabine ...

    Clinical Trial last updated 04/27/2016 - 10:46am.

  4. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... has been shown that about 30% of patients do not respond to immunosuppressive therapy or experience recurrence, and graft rejection and ... Associated Drug(s):  Eltrombopag ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  5. Eltrombopag now an approved therapy for certain patients with severe aplastic anemia

    ... anemia (SAA) who have had an insufficient response to immunosuppressive therapy and are not candidates for a hematopoietic stem ... for SAA is significant because “This is the first new drug approved for aplastic anemia since ATG, and it is the first drug ever ...

    Page last updated 08/27/2014 - 2:19pm.

  6. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... (MDS) Associated Drug(s):  Cyclophosphamide ... tolerant of their grafts with no active GVHD requiring immunosuppressive therapy DONOR: Donors must be HLA-haploidentical ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  7. What are the treatments for PNH?

    ... to help reduce the chance of    having blood clots. Immunosuppressive therapy:  Lowers your body's immune response and is ... used. Eculizumab (Soliris®):  The only drug approved by the U.S. Food and Drug Administration (FDA) and the European ...

    FAQ last updated 03/15/2016 - 11:32pm.

  8. Prednisone

    ... be used to stop the effects of serum sickness after immunosuppressive therapy with ATG. Prednisone may also increase counts of ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 03/10/2016 - 11:27pm.

  9. Bone Marrow Transplant

    ... severe bone marrow failure that does not respond to immunosuppressive therapy or those patients with low platelet ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 03/29/2016 - 7:27pm.

  10. What are the treatments for MDS?

    ... may also include growth factors or iron chelation. Immunosuppressive therapy:  Consists of medicines to keep the immune system ... antithymocyte globulin ) and cyclosporine . Drug therapies:  Approved specifically to treat MDS, they work to stop ...

    FAQ last updated 03/15/2016 - 11:31pm.