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  1. PNH - Treatment (OLD)

    ... available. It was recently approved to treat PNH. This drug is Eltrombopag (Promacta ®), a synthetic drug that mimics thrombopoetin, ... given as first line treatment for PNH, along with standard immunosuppressive therapy with ATG and cyclosporine . ...

    Topic section last updated 03/10/2016 - 11:09pm.

  2. Reduced Intensity Double Umbilical Cord Blood Transplantation

    ... body radiation on day 0 (same day as transplant) Immunosuppressive Therapy Tacrolimus and sirolimus beginning day -3, ... aplastic anemia Associated Drug(s):  Fludarabine ...

    Clinical Trial last updated 04/27/2016 - 10:46am.

  3. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... syndromes (MDS) Associated Drug(s):  Cyclophosphamide ... of the following: Greater than 1 cycle of induction therapy required to achieve remission Preceding myelodysplastic syndrome ... tolerant of their grafts with no active GVHD requiring immunosuppressive therapy DONOR: Donors must be HLA-haploidentical ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  4. Growth Factors

    ... in the bone marrow to stimulate. They may be used after immunosuppressive therapy is done and bone marrow stem cells start to come ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 04/06/2016 - 12:37pm.

  5. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... has been shown that about 30% of patients do not respond to immunosuppressive therapy or experience recurrence, and graft rejection and ... aplastic anemia Associated Drug(s):  Eltrombopag ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  6. What are the treatments for PNH?

    ... to help reduce the chance of    having blood clots. Immunosuppressive therapy:  Lowers your body's immune response and is ... used. Eculizumab (Soliris®):  The only drug approved by the U.S. Food and Drug Administration (FDA) and the European ...

    FAQ last updated 03/15/2016 - 11:32pm.

  7. Bone Marrow Transplant

    ... severe bone marrow failure that does not respond to immunosuppressive therapy or those patients with low platelet ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 03/29/2016 - 7:27pm.

  8. Prednisone

    ... be used to stop the effects of serum sickness after immunosuppressive therapy with ATG. Prednisone may also increase counts of ... other qualified health provider about your condition and any drug or other treatment you are considering. Make sure you fully understand all ...

    Topic section last updated 03/10/2016 - 11:27pm.

  9. What are the treatments for MDS?

    ... may also include growth factors or iron chelation. Immunosuppressive therapy:  Consists of medicines to keep the immune system ... antithymocyte globulin ) and cyclosporine . Drug therapies:  Approved specifically to treat MDS, they work to stop ...

    FAQ last updated 03/15/2016 - 11:31pm.

  10. Moderate, Severe, and Very Severe Aplastic Anemia: How are treatment decisions made?

    ... aplastic anemia. Does the advent of the newly approved drug eltrombopag (Promacta®) affect treatment decisions? It does, but at ... This is when there is no response or success from earlier immunosuppressive treatment. It should be distinguished from recurrent or ...

    Interview last updated 10/14/2015 - 12:47pm.