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  1. Eltrombopag restores tri-lineage hematopoiesis in refractory severe aplastic anemia which can be sustained on discontinuation of drug

    ... aplastic anemia (SAA) remain pancytopenic despite immunosuppressive therapy. We have previously demonstrated that eltrombopag has ... patients with robust near-normalization of blood counts had drug discontinued at a median of 28.5 months after entry (range 9 to 37), and ...

    Research Article last updated 01/07/2014 - 12:22pm.

  2. Immunosuppressive Therapy

    ... older patients with acquired aplastic anemia , immunosuppressive drug therapy is the treatment of choice. It is also used for aplastic ...

    Topic section last updated 04/01/2016 - 2:24pm.

  3. Eltrombopag in aplastic anemia

    ... The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and ... refractory to IST. There is evidence that this drug works by directly stimulating marrow stem and progenitor cells thereby ...

    Research Article last updated 03/02/2015 - 12:51pm.

  4. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... Journal Title:  Curr Drug Targets Primary Author:  ... marrow. Historically the two treatments option have been immunosuppressive therapy (IST) and bone marrow transplantation (HSCT) ...

    Research Article last updated 03/03/2015 - 11:27am.

  5. How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromes.

    ... of the disease. Three drugs are now specifically Food and Drug Administration-approved for treatment of MDS: (1) azacitidine , ... results with each of these agents, plus results with immunosuppressive therapy, are reviewed to guide clinical decision making. ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. AAMDSIF Caitlyn Langley Research Fund

    ... October, 2001 when she was 5 years old. After years of immunosuppressive drug therapy , Caitlyn is feeling well. Today, Caitlyn is an active teenager ...

    Research Fund last updated 06/08/2017 - 3:28pm.

  7. Simona Pagliuca, MD

    ... allogeneic hematopoietic stem cell transplantation and immunosuppressive therapy based on two drugs: " cyclosporine " and ... results of standard therapy, by association with an other drug, called "eltrombopag". Researchers want to answer a simple question: Which ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  8. Eltrombopag Added to IST Yields Encouraging Results

    ... that stimulating remaining stem cells with a drug that mimics the actions of a natural growth substance for marrow stem ... frequency in patients who had not adequately responded to immunosuppressive therapy (IST). These refractory patients were ...

    Interview last updated 05/24/2017 - 7:44am.

  9. Judi Wilkinson

    ... Links Immunosuppressive drug therapy Bone marrow transplant ...

    "Like You" Patient Story last updated 06/01/2017 - 10:33am.

  10. Briana Donis

    ... Treatment Immunosuppressive therapy was the first course of treatment, but it didn’t ... Immunosuppressive drug therapy Bone marrow transplant ...

    "Like You" Patient Story last updated 04/28/2017 - 1:56pm.