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  1. Somatic HLA mutations expose the role of class I–mediated autoimmunity in aplastic anemia and its clonal complications

    ... pathogenesis is unknown, aAA is thought to be driven by human leukocyte antigen ( HLA )–restricted T cell immunity, with ...

    Research Article last updated 10/23/2017 - 10:56am.

  2. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... No suitable fully matched related (6/6 match for human leukocyte antigen ( HLA )-A and B at intermediate or high resolution ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  3. Stem Cell Transplantation: What Happens Behind the Scenes?

    ... registry, called Be the Match®.  We use HLA Typing – Human Leukocyte Antigen Typing – to match donors.  HLA is the part of your ...

    Interview last updated 01/18/2018 - 1:28pm.

  4. Daria Babushok, MD, PhD

    ... the cells to escape immune recognition through loss of Human Leukocyte Antigen ( HLA ) genes. The mutations were present in a ...

    Grant Recipient last updated 01/12/2018 - 9:44am.

  5. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... of the greater probability for eventual failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line ...

    Research Article last updated 11/01/2016 - 1:55pm.

  6. High-dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

    ... Children and adolescents with SAA who lacked an human leukocyte antigen -matched sibling donor were treated with cyclophosphamide ...

    Research Article last updated 11/01/2016 - 1:49pm.

  7. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... of the greater probability for eventual failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line ...

    Research Article last updated 10/06/2016 - 9:48am.

  8. High-dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

    ... Children and adolescents with SAA who lacked an human leukocyte antigen -matched sibling donor were treated with cyclophosphamide ...

    Research Article last updated 08/15/2016 - 11:49am.

  9. Biomarkers for predicting clinical response to immunosuppressive therapy in aplastic anemia

    ... currently based on patient age and the availability of a human leukocyte antigen ( HLA )-matched donor. Although IST is a promising ...

    Research Article last updated 06/22/2016 - 10:19am.

  10. Alternative donor transplants for severe aplastic anemia: current experience

    ... severe aplastic anemia (SAA), who lack a human leukocyte antigen ( HLA ) identical sibling donor (SIB), have two ...

    Research Article last updated 06/07/2016 - 10:52am.