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  1. Myelodysplastic Syndromes and autoimmune disorders: Cause or consequence?

    ... seronegative arthritis, panarteritis nodosa, autoimmune hemolysis , and pernicious anemia . Those with both MDS and AD ...

    Research Review last updated 05/02/2016 - 9:18am.

  2. Special Issues for People with PNH

    ... , there are also a few case reports of flares of hemolysis (when red blood cells are destroyed) after receiving a flu shot. ... are not the same as randomized clinical trials, one case of hemolysis was severe enough to put the patient in the hospital. Thus some ...

    Page last updated 01/20/2015 - 4:59pm.

  3. PNH - Basics

    ... cells to break apart. Doctors call this breaking apart " hemolysis ." It happens because the surface of a person’s blood cells ...

    Topic section last updated 04/05/2016 - 4:02pm.

  4. Eculizumab

    ... Reduce the breaking apart of red blood cells ( hemolysis ) over both the short and the long term Reduce the risk of blood ...

    Topic section last updated 03/29/2016 - 7:20pm.

  5. Eculizumab

    ... system, to be less active. By doing this it reduces hemolysis , the destruction of red blood cells, in patients with PNH. It is ...

    Drug last updated 03/24/2016 - 12:32pm.

  6. Diagnosis

    ... blood can mean that red blood cells are breaking apart ( hemolysis ) or that there is tissue damage in the body. It is important for ...

    Topic section last updated 03/10/2016 - 11:04pm.

  7. Insights into the Natural History of Paroxysmal Nocturnal Hemoglobinuria (PNH): Analysis of the Presenting Clinical, Haematological and Flow Cytometric Features of 705 Patients Leads to Improved Classification and Prediction of Clinical Course

    ... Only 10 of 154 patients with aplastic anemia developed hemolysis (premature destruction of red blood cells), and all of these ... that were larger than 5%. In 44% of patients with hemolysis when they entered the study, PNH white blood cell clones continued to ...

    Research Review last updated 05/02/2016 - 9:20am.

  8. What are the treatments for PNH?

    ... , which is part of your immune system. This reduces hemolysis , the destruction of red blood cells. Bone marrow/stem cell ...

    FAQ last updated 03/15/2016 - 11:32pm.

  9. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... may be included at the discretion of the PI or where hemolysis has been excluded Availability of an 6/6 HLA matched ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  10. A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

    ... bilirubin within institutional limits unless due to hemolysis , Gilbert's syndrome, or ineffective erythropoiesis. ...

    Clinical Trial last updated 06/03/2016 - 3:09pm.