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  1. Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.

    ... lactate dehydrogenase , nor did they experience hemolysis or thrombosis , and they did not require specific ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Paroxysmal nocturnal hemoglobinuria from bench to bedside

    ... on the surface of PNH cells leads to complement-mediated hemolysis . The release of free hemoglobin leads to scavenging of ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. A closer look at paroxysmal nocturnal hemoglobinuria

    ... in the past two decades. The associated intravascular hemolysis , hypercoagulablilty, and bone marrow failure result in a ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Cerebral venous thrombosis in paroxysmal nocturnal hemoglobinuria: a series of 15 cases and review of the literature

    ... investigating PNH in case of cytopenia , hemolysis , abdominal veins thrombosis, or aplastic anemia history ...

    Research Article last updated 03/02/2015 - 11:38am.

  5. Patrizia Ricci, PhD

    ... destruction of red blood cells (intravascular hemolysis ), poor functioning of bone marrow , and thrombosis ... premature death of the red blood cells, a process called hemolysis , which results in severe anemia and contributes to a high ...

    Grant Recipient last updated 09/14/2016 - 2:42pm.

  6. PNH - Treatment (OLD)

    ... Iron Therapy Hemolysis can lead to a shortage of iron in your body. This can make it ... iron you need.  At first, taking iron pills can cause hemolysis, which can lead to dark urine. This happens because your bone marrow ...

    Topic section last updated 03/10/2016 - 11:09pm.

  7. AA&MDSIF announces PNH grant awards

    ... three major limitations of PNH treatment: continued hemolysis while on eculizumab; inconvenience of intravenous infusions; and ...

    Article last updated 12/14/2016 - 11:41am.

  8. Interviews with the Experts: The Complement System in PNH

    ... escapes the cell walls. This is the point where hemolysis occurs. Eventually the cell completely ruptures, releasing all ... PNH? In its normal form, patients present with overt hemolysis and hemoglobinuria. Subclinical PNH implies that you have a PNH ...

    Interview last updated 08/31/2016 - 8:39am.

  9. PNH: Treatments

    ... PNH went away on its own over time. Treating Hemolysis and Anemia For most people with PNH, the most common problem is anemia caused by hemolysis. Here are some treatments for hemolysis and anemia. Blood ...

    Page last updated 01/20/2015 - 4:48pm.

  10. Prednisone

    ... Prednisone is a steroid that can decrease hemolysis caused by PNH. It may make the complement system less ... platelets in some people. Prednisone does not stop all hemolysis, however. And it does have a lot side effects, especially if taken ...

    Page last updated 01/20/2015 - 4:57pm.