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  1. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... liver function: bilirubin >2.5 mg/dl (not due to hemolysis , Gilbert's or primary malignancy), AST/ALT > 3X ULN Poor ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  2. Disease Won't Run My Life

    ... to my PNH, my red blood cells had been merrily bursting ( hemolysis ), with no concern for me.  Occasionally, I was having PNH ...

    Patient Chronicle last updated 05/10/2016 - 3:36pm.

  3. Immunosuppression and Stem Cell Transplantation – How Are These Treatments Chosen?

    ... because there are several manifestations of it – hemolysis , thrombosis , and bone marrow failure. Bone marrow failure ... to reduce the risk of thrombosis (blood clots) and reduce hemolysis. This treatment is not curative and is often given for an extended ...

    Interview last updated 07/15/2015 - 10:19am.

  4. Transplantation Update

    ... in related or unrelated donors. PNH with prominent hemolysis is treated effectively, in most patients, with eculizumab ... anemia. Results are inferior in patients with severe hemolysis or thrombotic complications. Outcome tends to be better with HLA ...

    Interview last updated 05/14/2015 - 2:42pm.

  5. Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

    ... beyond 1.5 x ULN due to documented Gilbert's syndrome or hemolysis may be included). No detectable PNH ( paroxysmal nocturnal ...

    Clinical Trial last updated 05/02/2016 - 2:31pm.

  6. FAQs

    ... (a part of your immune system) less active. This reduces hemolysis , the destruction of red blood cells. Bone marrow/stem cell ...

    Topic section last updated 03/02/2016 - 11:42am.

  7. The Pathologist’s Role in an MDS Diagnosis

    ... There are situations when there is an associated hemolysis , or the bone marrow is obtained after repeated transfusions, ...

    Interview last updated 01/28/2014 - 1:47pm.

  8. Conferences, Webinars and Webcasts

    ... to break apart. Doctors call this breaking apart " hemolysis ". It happens because your blood cells are missing a protein that ...

    Page last updated 09/30/2014 - 11:50am.

  9. Issues for Parents of Pediatric Bone Marrow Failure Patients

    ... marrow failure but very much the symptoms of PNH, the hemolysis , the unrelenting high LDH, the anemia; those people I would treat ...

    Page last updated 06/20/2011 - 12:10pm.