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  1. Detection of paroxysmal nocturnal hemoglobinuria clones to exclude inherited bone marrow failure syndromes

    ... None of the IBMSF patients had paroxysmal nocturnal hemoglobinuria (PNH) clones. CONCLUSIONS: Although further ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 04/09/2014 - 9:04am.

  2. Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study.

    ... BA21. Aplastic anemia , paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome are bone marrow failure ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/30/2012 - 2:51pm.

  3. Paroxysmal nocturnal hemoglobinuria clones in children with acquired aplastic anemia: a multicentre study

    ... >10%, and laboratory signs of hemolysis without hemoglobinuria were considered affected by paroxysmal nocturnal hemoglobinuria (PNH) secondary to AA; no thrombotic event was reported. ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 08/04/2014 - 8:16am.

  4. Paroxysmal Nocturnal Hemoglobinuria: From Bench to Bed

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia with highly ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/28/2016 - 11:40am.

  5. Predictors of Hemoglobin Response to Eculizumab Therapy in Paroxysmal Nocturnal Hemoglobinuria

    ... Paroxysmal nocturnal hemoglobinuria is a clonal, hematopoietic stem cell disorder that manifests ... is efficacious in patients with paroxysmal nocturnal hemoglobinuria, but responses can vary and may depend on underlying marrow ...

    Research Article last updated 11/05/2012 - 10:28am.

  6. The dysfunction of platelets in paroxysmal nocturnal hemoglobinuria

    ... is a dangerous complication of paroxysmal nocturnal hemoglobinuria (PNH) and has a high mortality rate. However, the mechanism ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:37am.

  7. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disease of hematopoietic stem cell ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:41am.

  8. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) are limited. We describe the safety and effectiveness ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:39am.

  9. Eculizumab in the management of paroxysmal nocturnal hemoglobinuria: patient selection and special considerations

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal disorder resulting from ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 09/13/2016 - 1:53pm.

  10. Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

    ... shown to prevent complications of paroxysmal nocturnal hemoglobinuria (PNH) and improve quality of life and overall survival, but ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 10/12/2015 - 10:05am.