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  1. Predictors of Hemoglobin Response to Eculizumab Therapy in Paroxysmal Nocturnal Hemoglobinuria

    ... Paroxysmal nocturnal hemoglobinuria is a clonal, hematopoietic stem cell disorder that manifests ... is efficacious in patients with paroxysmal nocturnal hemoglobinuria, but responses can vary and may depend on underlying marrow ...

    Research Article last updated 11/05/2012 - 10:28am.

  2. Serologic response to meningococcal vaccination in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with the terminal complement inhibitor eculizumab

    ... of patients with symptomatic paroxysmal nocturnal hemoglobinuria (PNH). Due to inhibition of terminal complement cascade, ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 02/03/2017 - 11:21am.

  3. Bilateral central serous retinopathy in a patient with paroxysmal nocturnal hemoglobinuria treated with deferoxamine

    ... therapy in the context of paroxysmal nocturnal hemoglobinuria . METHODS: Spectral-domain optical coherence ... RESULTS: A 76-year-old man with paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis was started on deferoxamine for ...

    Research Article last updated 11/02/2016 - 10:36am.

  4. Joint study by AAMDSIF/NORD on PNH

    ... Path to Diagnosis of Paroxysmal Nocturnal Hemoglobinuria Article Source:  ... Paroxysmal Nocturnal Hemoglobinuria has an adverse impact on patients’morbidity and mortality, ...

    Article last updated 11/14/2017 - 1:27pm.

  5. Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders

    ... damage in several human diseases. Paroxysmal nocturnal hemoglobinuria (PNH) may be considered the paradigm a disease caused by ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 10/02/2012 - 10:00am.

  6. Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

    ... shown to prevent complications of paroxysmal nocturnal hemoglobinuria (PNH) and improve quality of life and overall survival, but ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 10/12/2015 - 10:05am.

  7. Paroxysmal Nocturnal Hemoglobinuria: From Bench to Bed

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia with highly ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/28/2016 - 11:40am.

  8. The dysfunction of platelets in paroxysmal nocturnal hemoglobinuria

    ... is a dangerous complication of paroxysmal nocturnal hemoglobinuria (PNH) and has a high mortality rate. However, the mechanism ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:37am.

  9. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disease of hematopoietic stem cell ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:41am.

  10. Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan

    ... eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) are limited. We describe the safety and effectiveness ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/02/2016 - 10:39am.