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  1. Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia

    ... peripheral blood cytopenias. Minor paroxysmal nocturnal hemoglobinuria populations and a short telomere length were ... to immunosuppressive therapy. The paroxysmal nocturnal hemoglobinuria populations and telomere length were detected by flow ...

    Research Article last updated 10/12/2015 - 10:20am.

  2. Small-molecule Factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

    ... Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of ... and moreover some patients with paroxysmal nocturnal hemoglobinuria on eculizumab have symptomatic extravascular hemolysis , ...

    Research Article last updated 11/28/2016 - 11:42am.

  3. Update on the diagnosis and management of paroxysmal nocturnal hemoglobinuria

    ... Once suspected, the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) is straightforward when flow cytometric analysis of ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 01/26/2017 - 11:03am.

  4. Serologic response to meningococcal vaccination in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with the terminal complement inhibitor eculizumab

    ... of patients with symptomatic paroxysmal nocturnal hemoglobinuria (PNH). Due to inhibition of terminal complement cascade, ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 02/03/2017 - 11:21am.

  5. Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

    ... diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria for validation of high-sensitivity flow cytometry ... for diagnosis and/or monitoring of paroxysmal nocturnal hemoglobinuria. Results:: Implementation of technical advances reduced ...

    Research Article last updated 11/02/2016 - 10:42am.

  6. Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations

    ... a potential treatment option for paroxysmal nocturnal hemoglobinuria , a rare hematological disorder characterized by ... aplastic anemia paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 11/03/2014 - 10:22am.

  7. Bilateral central serous retinopathy in a patient with paroxysmal nocturnal hemoglobinuria treated with deferoxamine

    ... therapy in the context of paroxysmal nocturnal hemoglobinuria . METHODS: Spectral-domain optical coherence ... RESULTS: A 76-year-old man with paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis was started on deferoxamine for ...

    Research Article last updated 11/02/2016 - 10:36am.

  8. Successful Use of Eculizumab in a Pediatric Patient Treated for Paroxysmal Nocturnal Hemoglobinuria

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, debilitating life-threatening clonal ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/31/2012 - 12:38pm.

  9. Eculizumab: a guide to its use in paroxysmal nocturnal hemoglobinuria

    ... hemolysis in patients with paroxysmal nocturnal hemoglobinuria (PNH), as well as stabilizing hemoglobin levels, ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/30/2012 - 2:23pm.

  10. Paroxysmal nocturnal hemoglobinuria

    ... BA21. Aplastic anemia , paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome are bone marrow failure ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/30/2012 - 2:21pm.