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  1. Can iron overload in patients with lower-risk myelodysplastic syndromes be reduced using erythropoiesis-stimulating agents?

    ... significant association between ESA response, post-ESA hemoglobin ≥100 g/L, and post-ESA ferritin <1000 ng/mL (P = 0.0003 ...

    Research Article last updated 12/09/2015 - 8:52am.

  2. What are the different components of blood?

    ... up almost half of blood. Red blood cells are filled with hemoglobin . That's a protein that picks up oxygen in the lungs and brings ...

    FAQ last updated 01/04/2018 - 12:05pm.

  3. Clinical outcome after failure of hypomethylating therapy for myelodysplastic syndromes

    ... in the first cohort of patients the goal is to improve hemoglobin levels and the quality of life while in higher risk patients ...

    Research Article last updated 03/03/2015 - 12:40pm.

  4. Short- and long-term benefits of lenalidomide treatment in patients with lower-risk del(5q) myelodysplastic syndromes

    ... and time to AML progression. Achievement of RBC-TI and hemoglobin response was additionally associated with HRQOL benefits. ...

    Research Article last updated 12/08/2015 - 1:06pm.

  5. Self-perception of symptoms of anemia and fatigue before and after blood transfusions in patients with myelodysplastic syndromes

    ... was found between increments in the FACT-An score and hemoglobin value (rs 0.66, p = 0.02). One of seven items measuring ...

    Research Article last updated 01/20/2015 - 1:01pm.

  6. Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition

    ... intravascular and extravascular hemolysis . Free hemoglobin leads to nitric oxide depletion that mediates the ...

    Research Article last updated 11/05/2013 - 12:37pm.

  7. Thrombosis in paroxysmal nocturnal hemoglobinuria.

    ... include platelet activation, toxicity of free hemoglobin , nitric oxide depletion, absence of other GPI-linked ...

    Research Article last updated 05/14/2013 - 3:29pm.

  8. Prognostic Factors Associated With Disease Progression and Overall Survival in Patients With Myelodysplastic Syndromes Treated With Decitabine.

    ... study effect was associated with progression to AML. A hemoglobin value at least 10 g/dL, platelet count at least 50 × ...

    Research Article last updated 01/02/2013 - 2:53pm.

  9. Eculizumab: a guide to its use in paroxysmal nocturnal hemoglobinuria

    ... hemoglobinuria (PNH), as well as stabilizing hemoglobin levels, improving fatigue and health-related quality of life, ...

    Research Article last updated 07/30/2012 - 2:23pm.

  10. Asymptomatic cerebral bleeds in patients with aplastic anemia.

    ... of complete blood counts at the time of diagnosis were hemoglobin 5.7 gm/dl (range 2.5-9.2 gm/dl), white cell count 2,320/μl ...

    Research Article last updated 06/15/2012 - 2:46pm.