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  1. Epigenetics in focus: Pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents

    ... may reprogram the "methylome" while re-establishing hematopoiesis . Bone Marrow Diseases:  ...

    Research Article last updated 08/06/2013 - 2:48pm.

  2. Combination of Azacitidine and Lenalidomide in Myelodysplastic Syndromes or acute Myeloid Leukemia-a wise Liaison?

    ... the positive effects of each drug on the defective hematopoiesis while sparing potential side effects and toxicities. ...

    Research Article last updated 06/20/2013 - 11:05am.

  3. Immunomodulatory Drugs: New Options for the Treatment of Myelodysplastic Syndromes

    ... adult hematologic disorders characterized by ineffective hematopoiesis with progressive cytopenia and a risk of evolving ...

    Research Article last updated 01/03/2013 - 9:57am.

  4. Emerging immunosuppressive drugs in myelodysplastic syndromes

    ... by dysplastic morphologic features and ineffective hematopoiesis . Pathophysiological characteristics change over time making ...

    Research Article last updated 01/03/2013 - 9:54am.

  5. Interpreting new molecular genetics in myelodysplastic syndromes

    ... group of clonal diseases characterized by ineffective hematopoiesis , peripheral blood cytopenias, and an increased risk of ...

    Research Article last updated 01/02/2013 - 2:59pm.

  6. Myelodysplastic syndrome hematopoietic stem cell

    ... (HSC) malignancies that are characterized by ineffective hematopoiesis and frequent progression to acute myeloid leukemia (AML). ...

    Research Article last updated 11/05/2012 - 10:21am.

  7. Last Marrow Standing: Bone Marrow Transplantation for Acquired Bone Marrow Failure Conditions

    ... immune dysregulation and the development of abnormal hematopoiesis . Allogeneic hematopoietic cell transplantation plays a ...

    Research Article last updated 11/05/2012 - 10:06am.

  8. Immunomodulatory treatment of myelodysplastic syndromes: antithymocyte globulin, cyclosporine, and alemtuzumab

    ... forms of IST have been successfully used to restore hematopoiesis in MDS in many centers worldwide. In this review we outline ...

    Research Article last updated 11/05/2012 - 9:48am.

  9. Revisiting use of growth factors in myelodysplastic syndromes

    ... characterized by morphologic dysplasia, aberrant hematopoiesis and peripheral blood refractory cytopenias. MDS is ...

    Research Article last updated 07/31/2012 - 12:57pm.

  10. Molecular and genetic features of myelodysplastic syndromes.

    ... final common pathogenetic pathway causing ineffective hematopoiesis in MDS has been the varying degrees of apoptosis of ...

    Research Article last updated 04/24/2012 - 2:43pm.