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  1. Paroxysmal Nocturnal Hemoglobinuria (PNH)

    ... Formed? The process of making blood cells is called hematopoiesis . Blood cells are made in the bone marrow , a spongy tissue ...

    Page last updated 09/30/2017 - 11:34am.

  2. Aplastic anemia and clonal evolution: germ line and somatic genetics

    ... in marrow failure revealed a high frequency of clonal hematopoiesis with the acquisition of mutations in genes associated with ...

    Research Article last updated 01/24/2017 - 12:41pm.

  3. Kate MacNamara, PhD

    ... identify novel pathways that can be targeted to rescue hematopoiesis in patients with bone marrow failure. ... macrophages drive the loss of hematopoietic cells and hematopoiesis . ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  4. Implications of molecular genetic diversity in myelodysplastic syndromes

    ... with unexplained cytopenias have a high rate of clonal hematopoiesis that may be an important risk factor to identify clinically. ...

    Research Article last updated 12/09/2016 - 2:54pm.

  5. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... for the article is: Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia Matthew J. Olnes, M.D., ... Dunbar, M.D., is head of the Laboratory of Molecular Hematopoiesis in the Hematology Branch at the National Heart, Lung, and ...

    Interview last updated 07/06/2012 - 3:42pm.

  6. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... AA. It has demonstrated efficacy in restoring trilineage hematopoiesis , and this positive effect continues after discontinuation of ...

    Research Article last updated 11/01/2016 - 2:01pm.

  7. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... clonal stem cell disorders characterized by ineffective hematopoiesis , cytopenias and a risk of progression to acute myeloid ...

    Research Article last updated 10/06/2016 - 1:01pm.

  8. Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study.

    ... in which outgrowth of neoplastic clones disrupts normal hematopoiesis . Some patients with unexplained persistent cytopenias may not ...

    Research Article last updated 09/19/2016 - 11:05am.

  9. Analysis of allogeneic hematopoietic stem cell transplantation with high-dose cyclophosphamide-induced immune tolerance for severe aplastic anemia

    ... was confirmed by the evidence of 100 % donor hematopoiesis ; T lymphocyte subset counts also increased ...

    Research Article last updated 11/01/2016 - 1:59pm.

  10. Deregulated microRNA expression and its pathogenetic implications for myelodysplastic syndromes

    ... stem cell disorders characterized by ineffective hematopoiesis , cytopenias. MicroRNAs (miRNAs) are short non-coding RNA ...

    Research Article last updated 08/15/2016 - 11:30am.