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  1. MDS - Basics

    ... The process of making blood cells is called hematopoiesis . Blood cells are made in the bone marrow , a spongy ...

    Topic section last updated 06/12/2018 - 12:47pm.

  2. Top honor goes to AAMDSIF Medical Advisor

    ... myeloma. Recent studies have characterized clonal hematopoiesis and its contribution to both hematologic malignancies and ... Award, and the International Society for Experimental Hematopoiesis Till and McCullough Award. “The Society is honored ...

    Article last updated 08/29/2017 - 7:54am.

  3. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... for the article is: Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia Matthew J. Olnes, M.D., ... Dunbar, M.D., is head of the Laboratory of Molecular Hematopoiesis in the Hematology Branch at the National Heart, Lung, and ...

    Interview last updated 07/06/2012 - 3:42pm.

  4. Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

    ... that are characterized by defective bone marrow hematopoiesis and by the occurrence of intramedullary apoptosis . ... that the dysregulation of these molecules leads to abnormal hematopoiesis, unbalanced cell death and proliferation in patients' bone marrow ...

    Research Article last updated 06/21/2017 - 11:10am.

  5. An exploratory clinical trial of bortezomib in patients with lower risk myelodysplastic syndromes

    ... syndromes (MDSs) are characterized by ineffective hematopoiesis and an increased risk of transformation. Few effective ...

    Research Article last updated 05/02/2017 - 10:33am.

  6. Aplastic anemia

    ... and aplastic anemia-specific therapy aimed at restoring hematopoiesis . Supportive therapies include transfusion, G-CSF, and the ... Although transplantation provides complete recovery of hematopoiesis (cure), there is a risk of death due to transplant-related ...

    Research Article last updated 11/01/2016 - 1:58pm.

  7. Lenalidomide use in myelodysplastic syndromes: Insights into the biologic mechanisms and clinical applications

    ... of clonal myeloid neoplasms characterized by ineffective hematopoiesis leading to blood cytopenias and a variable risk of ...

    Research Article last updated 02/21/2017 - 9:34am.

  8. Functional characteristics of mesenchymal stem cells derived from bone marrow of patients with myelodysplastic syndromes

    ... of their capabilities of immunomodulatory and supporting hematopoiesis . Nevertheless, it is unclear whether the characteristics of ... appeared to be impaired in immunomodulatory and supporting hematopoiesis function. Although, MDS-MSCs could express hematopoietic ...

    Research Article last updated 04/24/2012 - 2:10pm.

  9. Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results

    ... stem cells (MSCs) have been shown to support hematopoiesis in vivo and to display potent immunosuppressive effects to ...

    Research Article last updated 02/01/2017 - 12:30pm.

  10. Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016

    ... marrow failure syndromes (BMFS) have ineffective hematopoiesis due to impairments of the hematopoietic stem cell ...

    Research Article last updated 01/24/2017 - 11:54am.